Chad E Cragle
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Explore the profile of Chad E Cragle including associated specialties, affiliations and a list of published articles.
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9
Citations
119
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Recent Articles
1.
Chang C, Unruh K, Cragle C, Moonka R
J Surg Case Rep
. 2024 Sep;
2024(9):rjae596.
PMID: 39314782
Colouterine fistulas are generally seen in post-menopausal patients and present with abdominal pain and non-physiologic vaginal drainage. A history of uterine pathology or diverticulitis is generally lacking. Visualization of the...
2.
Cragle C, Schlenker J, Moonka R, Wiebusch A, Simianu V
J Surg Case Rep
. 2022 Aug;
2022(7):rjac318.
PMID: 35919701
A 68-year-old man presented with septic shock and severe perineal pain from a perforated low-rectal cancer causing a perineal necrotizing soft tissue infection. He underwent laparoscopic diverting colostomy and multiple...
3.
Cragle C, MacNicol M, Byrum S, Hardy L, Mackintosh S, Richardson W, et al.
J Biol Chem
. 2019 Jun;
294(28):10969-10986.
PMID: 31152063
The Musashi family of mRNA translational regulators controls both physiological and pathological stem cell self-renewal primarily by repressing target mRNAs that promote differentiation. In response to differentiation cues, Musashi can...
4.
MacNicol M, Cragle C, McDaniel F, Hardy L, Wang Y, Arumugam K, et al.
Sci Rep
. 2017 Sep;
7(1):11503.
PMID: 28912529
The Musashi family of RNA binding proteins act to promote stem cell self-renewal and oppose cell differentiation predominantly through translational repression of mRNAs encoding pro-differentiation factors and inhibitors of cell...
5.
MacNicol M, Cragle C, Arumugam K, Fosso B, Pesole G, MacNicol A
Biomolecules
. 2015 Jul;
5(3):1580-99.
PMID: 26197342
Regulated mRNA translation plays a key role in control of cell cycle progression in a variety of physiological and pathological processes, including in the self-renewal and survival of stem cells...
6.
Penthala N, Bommagani S, Janganati V, MacNicol K, Cragle C, Madadi N, et al.
Eur J Med Chem
. 2014 Aug;
85:517-25.
PMID: 25117652
(E)-13-(Aryl/heteroaryl)parthenolides (5a-i and 6a-i) were synthesized and evaluated for their ability to modify cell cycle progression during progesterone-stimulated Xenopus oocyte maturation and screened for their anticancer activity against a panel...
7.
Janganati V, Penthala N, Cragle C, MacNicol A, Crooks P
Bioorg Med Chem Lett
. 2014 Mar;
24(8):1963-7.
PMID: 24656611
Aminoparthenolide derivatives have been prepared by reaction of parthenolide with various heterocyclic amines to afford corresponding Michael addition products. These novel compounds were evaluated for their modulatory effects on Xenopus...
8.
Arumugam K, MacNicol M, Wang Y, Cragle C, Tackett A, Hardy L, et al.
J Biol Chem
. 2012 Jan;
287(13):10639-10649.
PMID: 22215682
Cell cycle re-entry during vertebrate oocyte maturation is mediated through translational activation of select target mRNAs, culminating in the activation of mitogen-activated protein kinase and cyclin B/cyclin-dependent kinase (CDK) signaling....
9.
MacNicol M, Cragle C, MacNicol A
Cell Cycle
. 2010 Dec;
10(1):39-44.
PMID: 21191181
Musashi-mediated mRNA translational control has been implicated in the promotion of physiological and pathological stem cell proliferation. During self-renewal of mammalian stem cells, Musashi has been proposed to act to...