Angus M MacNicol
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Explore the profile of Angus M MacNicol including associated specialties, affiliations and a list of published articles.
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39
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734
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Recent Articles
1.
Miles T, Odle A, Byrum S, Lagasse A, Haney A, Ortega V, et al.
Endocrinology
. 2025 Feb;
PMID: 39964842
Anterior pituitary somatotropes respond to metabolic signals from the adipokine leptin to optimize functional responses to the body's nutritional state via growth hormone (GH) secretion. Molecular targets of leptin in...
2.
Miles T, Allensworth-James M, Odle A, Silva Moreira A, Haney A, Lagasse A, et al.
Front Endocrinol (Lausanne)
. 2024 May;
14:1332959.
PMID: 38720938
Maternal nutrition during embryonic development and lactation influences multiple aspects of offspring health. Using mice, this study investigates the effects of maternal caloric restriction (CR) during mid-gestation and lactation on...
3.
Banik J, Silva Moreira A, Lim J, Tomlinson S, Hardy L, Lagasse A, et al.
Sci Rep
. 2024 Mar;
14(1):5918.
PMID: 38467682
The pituitary functions as a master endocrine gland that secretes hormones critical for regulation of a wide variety of physiological processes including reproduction, growth, metabolism and stress responses. The distinct...
4.
Miles T, Odle A, Byrum S, Lagasse A, Haney A, Ortega V, et al.
Endocrinology
. 2023 Dec;
165(2).
PMID: 38103263
Anterior pituitary cell function requires a high level of protein synthesis and secretion which depend heavily on mitochondrial adenosine triphosphate production and functional endoplasmic reticula. Obesity adds stress to tissues,...
5.
Silva Moreira A, Lim J, Urbaniak A, Banik J, Bronson K, Lagasse A, et al.
Endocrinology
. 2023 Jul;
164(9).
PMID: 37477898
The anterior pituitary controls key biological processes, including growth, metabolism, reproduction, and stress responses through distinct cell types that each secrete specific hormones. The anterior pituitary cells show a remarkable...
6.
Urbaniak A, Reed M, Heflin B, Gaydos J, Pina-Oviedo S, Jedrzejczyk M, et al.
Biomed Pharmacother
. 2022 Sep;
153:113440.
PMID: 36076555
Glioblastoma (GBM) remains the most frequently diagnosed primary malignant brain cancer in adults. Despite recent progress in understanding the biology of GBM, the clinical outcome for patients remains poor, with...
7.
Urbaniak A, Reed M, Fil D, Moorjani A, Heflin S, Antoszczak M, et al.
Biomed Pharmacother
. 2021 Jun;
141:111815.
PMID: 34130123
Breast cancer remains one of the leading cancers among women. Cancer stem cells (CSCs) are tumor-initiating cells which drive progression, metastasis, and reoccurrence of the disease. CSCs are resistant to...
8.
Odle A, MacNicol M, Childs G, MacNicol A
Int J Mol Sci
. 2021 Apr;
22(7).
PMID: 33805020
The proper expression of gonadotropin-releasing hormone receptors (GnRHRs) by pituitary gonadotropes is critical for maintaining maximum reproductive capacity. GnRH receptor expression must be tightly regulated in order to maintain the...
9.
Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi
Allensworth-James M, Banik J, Odle A, Hardy L, Lagasse A, Silva Moreira A, et al.
Endocrinology
. 2020 Dec;
162(3).
PMID: 33373440
The adipokine leptin regulates energy homeostasis through ubiquitously expressed leptin receptors. Leptin has a number of major signaling targets in the brain, including cells of the anterior pituitary (AP). We...
10.
Childs G, Odle A, MacNicol M, MacNicol A
Endocrinology
. 2020 Nov;
162(2).
PMID: 33165520
A healthy nutritional state is required for all aspects of reproduction and is signaled by the adipokine leptin. Leptin acts in a relatively narrow concentration range: too much or too...