Cedric Bosteels
Overview
Explore the profile of Cedric Bosteels including associated specialties, affiliations and a list of published articles.
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24
Citations
888
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Recent Articles
1.
Debeuf N, Deckers J, Lameire S, Bosteels C, Hammad H, Lambrecht B
Front Immunol
. 2024 Oct;
15:1439789.
PMID: 39439800
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a pleiotropic cytokine, able to promote both myelopoiesis and activation of immune cells. Particularly in the lung, GM-CSF plays an important homeostatic role in...
2.
Van Braeckel E, Bosteels C
Eur Respir Rev
. 2024 Jul;
33(173).
PMID: 38960614
Bronchiectasis and nontuberculous mycobacteria (NTM) are intricately intertwined, with NTM capable of being both a cause and consequence of bronchiectatic disease. This narrative review focuses on the common ground of...
3.
Van Damme K, Hoste L, Declercq J, De Leeuw E, Maes B, Martens L, et al.
Sci Transl Med
. 2023 Aug;
15(710):eadi0252.
PMID: 37611083
Improvements in COVID-19 treatments, especially for the critically ill, require deeper understanding of the mechanisms driving disease pathology. The complement system is not only a crucial component of innate host...
4.
Bosteels V, Marechal S, De Nolf C, Rennen S, Maelfait J, Tavernier S, et al.
Sci Immunol
. 2023 May;
8(83):eadd3955.
PMID: 37172103
Dendritic cells (DCs) mature in an immunogenic or tolerogenic manner depending on the context in which an antigen is perceived, preserving the balance between immunity and tolerance. Whereas the pathways...
5.
Bosteels C, Van Damme K, De Leeuw E, Declercq J, Maes B, Bosteels V, et al.
Cell Rep Med
. 2022 Dec;
3(12):100833.
PMID: 36459994
GM-CSF promotes myelopoiesis and inflammation, and GM-CSF blockade is being evaluated as a treatment for COVID-19-associated hyperinflammation. Alveolar GM-CSF is, however, required for monocytes to differentiate into alveolar macrophages (AMs)...
6.
De Leeuw E, Van Damme K, Declercq J, Bosteels C, Maes B, Tavernier S, et al.
Respir Res
. 2022 Aug;
23(1):202.
PMID: 35945604
Background: The efficacy and safety of complement inhibition in COVID-19 patients is unclear. Methods: A multicenter randomized controlled, open-label trial. Hospitalized COVID-19 patients with signs of systemic inflammation and hypoxemia...
7.
De Leeuw E, Bosteels C, Lambrecht B, Hammad H
Methods Mol Biol
. 2022 Jun;
2506:237-255.
PMID: 35771476
In the lungs, immune cells make contact with different antigens every day. This requires an adequate immune response. Dendritic cells (DCs) form a dense network in the respiratory mucosa and...
8.
Lorent N, Vande Weygaerde Y, Claeys E, Guler Caamano Fajardo I, De Vos N, De Wever W, et al.
ERJ Open Res
. 2022 Apr;
8(2).
PMID: 35415186
Background: Long-term outcome data of coronavirus disease 2019 (COVID-19) survivors are needed to understand their recovery trajectory and additional care needs. Methods: A prospective observational multicentre cohort study was carried...
9.
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C
Hoste L, Roels L, Naesens L, Bosteels V, Vanhee S, Dupont S, et al.
J Exp Med
. 2021 Dec;
219(2).
PMID: 34914824
In rare instances, pediatric SARS-CoV-2 infection results in a novel immunodysregulation syndrome termed multisystem inflammatory syndrome in children (MIS-C). We compared MIS-C immunopathology with severe COVID-19 in adults. MIS-C does...
10.
Declercq J, Van Damme K, De Leeuw E, Maes B, Bosteels C, Tavernier S, et al.
Lancet Respir Med
. 2021 Nov;
9(12):1427-1438.
PMID: 34756178
Background: Infections with SARS-CoV-2 continue to cause significant morbidity and mortality. Interleukin (IL)-1 and IL-6 blockade have been proposed as therapeutic strategies in COVID-19, but study outcomes have been conflicting....