Victor Bosteels
Overview
Explore the profile of Victor Bosteels including associated specialties, affiliations and a list of published articles.
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12
Citations
369
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Recent Articles
1.
Quintelier K, Willemsen M, Bosteels V, Aerts J, Saeys Y, Van Gassen S
Cytometry A
. 2025 Jan;
PMID: 39871681
Cytometry is a single cell, high-dimensional, high-throughput technique that is being applied across a range of disciplines. However, many elements alongside the data acquisition process might give rise to technical...
2.
Bosteels V, Janssens S
Nat Rev Immunol
. 2024 Sep;
25(2):125-140.
PMID: 39289483
Dendritic cells (DCs) are crucial gatekeepers of the balance between immunity and tolerance. They exist in two functional states, immature or mature, that refer to an information-sensing versus an information-transmitting...
3.
Wallaeys C, Garcia-Gonzalez N, Timmermans S, Vandewalle J, Vanderhaeghen T, De Beul S, et al.
Cell Host Microbe
. 2024 Sep;
32(10):1725-1743.e7.
PMID: 39243761
The cytokine tumor necrosis factor (TNF) plays important roles in limiting infection but is also linked to sepsis. The mechanisms underlying these paradoxical roles are unclear. Here, we show that...
4.
Bosteels V, Van Duyse J, Ruyssinck E, Van der Borght K, Nguyen L, Gavel J, et al.
Cytometry A
. 2024 Mar;
105(6):464-473.
PMID: 38456613
Over the past decade, the flow cytometry field has witnessed significant advancements in the number of fluorochromes that can be detected. This enables researchers to analyze more than 40 markers...
5.
Reuschle Q, Van Heddegem L, Bosteels V, Moncan M, Depauw S, Wadier N, et al.
J Autoimmun
. 2023 Dec;
142:103152.
PMID: 38071801
Anti-nuclear antibodies are the hallmark of autoimmune diseases such as systemic lupus erythematosus (SLE) and scleroderma. However, the molecular mechanisms of B cell tolerance breakdown in these pathological contexts are...
6.
Bosteels V, Marechal S, De Nolf C, Rennen S, Maelfait J, Tavernier S, et al.
Sci Immunol
. 2023 May;
8(83):eadd3955.
PMID: 37172103
Dendritic cells (DCs) mature in an immunogenic or tolerogenic manner depending on the context in which an antigen is perceived, preserving the balance between immunity and tolerance. Whereas the pathways...
7.
Bosteels C, Van Damme K, De Leeuw E, Declercq J, Maes B, Bosteels V, et al.
Cell Rep Med
. 2022 Dec;
3(12):100833.
PMID: 36459994
GM-CSF promotes myelopoiesis and inflammation, and GM-CSF blockade is being evaluated as a treatment for COVID-19-associated hyperinflammation. Alveolar GM-CSF is, however, required for monocytes to differentiate into alveolar macrophages (AMs)...
8.
Murgaski A, Kiss M, Van Damme H, Kancheva D, Vanmeerbeek I, Keirsse J, et al.
Cancer Res
. 2022 Aug;
82(20):3785-3801.
PMID: 35979635
Significance: This work highlights the temporal roles of different dendritic cell subsets in promoting CD8+ T-cell-driven responses to CD40 agonist therapy in cancer.
9.
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C
Hoste L, Roels L, Naesens L, Bosteels V, Vanhee S, Dupont S, et al.
J Exp Med
. 2021 Dec;
219(2).
PMID: 34914824
In rare instances, pediatric SARS-CoV-2 infection results in a novel immunodysregulation syndrome termed multisystem inflammatory syndrome in children (MIS-C). We compared MIS-C immunopathology with severe COVID-19 in adults. MIS-C does...
10.
Declercq J, Van Damme K, De Leeuw E, Maes B, Bosteels C, Tavernier S, et al.
Lancet Respir Med
. 2021 Nov;
9(12):1427-1438.
PMID: 34756178
Background: Infections with SARS-CoV-2 continue to cause significant morbidity and mortality. Interleukin (IL)-1 and IL-6 blockade have been proposed as therapeutic strategies in COVID-19, but study outcomes have been conflicting....