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Brian B Haab

Explore the profile of Brian B Haab including associated specialties, affiliations and a list of published articles. Areas
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Articles 80
Citations 2512
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Recent Articles
21.
Singh S, Pal K, Yadav J, Tang H, Partyka K, Kletter D, et al.
J Proteome Res . 2015 May; 14(6):2594-605. PMID: 25938165
The fucose post-translational modification is frequently increased in pancreatic cancer, thus forming the basis for promising biomarkers, but a subset of pancreatic cancer patients does not elevate the known fucose-containing...
22.
Kletter D, Curnutte B, Maupin K, Bern M, Haab B
Methods Mol Biol . 2015 Mar; 1273:203-14. PMID: 25753713
The glycan array is a powerful tool for investigating the specificities of glycan-binding proteins. By incubating a glycan-binding protein on a glycan array, the relative binding to hundreds of different...
23.
Tang H, Singh S, Partyka K, Kletter D, Hsueh P, Yadav J, et al.
Mol Cell Proteomics . 2015 Mar; 14(5):1323-33. PMID: 25733690
The sialyl-Lewis A (sLeA) glycan forms the basis of the CA19-9 assay and is the current best biomarker for pancreatic cancer, but because it is not elevated in ∼25% of...
24.
West M, Partyka K, Feasley C, Maupin K, Goppallawa I, West C, et al.
BMC Biotechnol . 2014 Dec; 14:101. PMID: 25479762
Background: γ-Glutamyl transpeptidase 1 (GGT1) is an N-glycosylated membrane protein that catabolizes extracellular glutathione and other γ-glutamyl-containing substrates. In a variety of disease states, including tumor formation, the enzyme is...
25.
Powers T, Neely B, Shao Y, Tang H, Troyer D, Mehta A, et al.
PLoS One . 2014 Sep; 9(9):e106255. PMID: 25184632
A recently developed matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) method to spatially profile the location and distribution of multiple N-linked glycan species in frozen tissues has been extended and...
26.
Sinha A, Cherba D, Bartlam H, Lenkiewicz E, Evers L, Barrett M, et al.
Mol Oncol . 2014 May; 8(7):1253-65. PMID: 24837184
The aggressiveness of pancreatic cancer is associated with the acquisition of mesenchymal characteristics by a subset of pancreatic cancer cells. The factors driving the development of this subset are not...
27.
Haab B, Partyka K, Cao Z
Curr Protoc Protein Sci . 2014 Feb; 73:27.6.1-27.6.16. PMID: 24510592
Antibody arrays provide a valuable method for obtaining multiple protein measurements from small volumes of biological samples. Antibody arrays can be designed to target not only core protein abundances (relative...
28.
Gbormittah F, Haab B, Partyka K, Garcia-Ott C, Hancapie M, Hancock W
J Proteome Res . 2013 Dec; 13(1):289-99. PMID: 24303806
Currently, pancreatic cancer is the fourth cause of cancer death. In 2013, it is estimated that ∼38 460 people will die of pancreatic cancer. Early detection of malignant cyst (pancreatic...
29.
McCarter C, Kletter D, Tang H, Partyka K, Ma Y, Singh S, et al.
Proteomics Clin Appl . 2013 Aug; 7(9-10):632-41. PMID: 23956151
Purpose: Lectins are valuable tools for detecting specific glycans in biological samples, but the interpretation of the measurements can be ambiguous due to the complexities of lectin specificities. Here, we...
30.
McWilliam H, Driguez P, Piedrafita D, Maupin K, Haab B, McManus D, et al.
Immunol Cell Biol . 2013 Jul; 91(7):477-85. PMID: 23856766
Schistosome parasites follow a complex migration path through various tissues, changing their antigenic profile as they develop. A thorough understanding of the antibody response in each tissue region could help...