Brian B Haab
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Explore the profile of Brian B Haab including associated specialties, affiliations and a list of published articles.
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2512
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Recent Articles
31.
Cao Z, Maupin K, Curnutte B, Fallon B, Feasley C, Brouhard E, et al.
Mol Cell Proteomics
. 2013 Jul;
12(10):2724-34.
PMID: 23836919
Specific protein glycoforms may be uniquely informative about the pathological state of a cyst and may serve as accurate biomarkers. Here we tested that hypothesis using antibody-lectin sandwich arrays in...
32.
Fallon B, Curnutte B, Maupin K, Partyka K, Choi S, Brand R, et al.
PLoS One
. 2013 Jun;
8(6):e65905.
PMID: 23750276
The development of accurate clinical biomarkers has been challenging in part due to the diversity between patients and diseases. One approach to account for the diversity is to use multiple...
33.
Kletter D, Singh S, Bern M, Haab B
Mol Cell Proteomics
. 2013 Feb;
12(4):1026-35.
PMID: 23399549
Lectin-glycan interactions have critical functions in multiple normal and pathological processes, but the binding partners and functions for many glycans and lectins are not known. An important step in better...
34.
Cao Z, Partyka K, McDonald M, Brouhard E, Hincapie M, Brand R, et al.
Anal Chem
. 2013 Jan;
85(3):1689-98.
PMID: 23286506
Improved methods for studying glycans could spur significant advances in the understanding and application of glycobiology. The use of affinity reagents such as lectins and glycan-binding antibodies is a valuable...
35.
Haab B
Proteomics Clin Appl
. 2012 Aug;
6(7-8):346-50.
PMID: 22927350
Carbohydrates have fundamental roles throughout biology, yet they have not been as well studied as proteins and nucleic acids, in part due to limitations in the experimental tools. Improved methods...
36.
Partyka K, Maupin K, Brand R, Haab B
Proteomics
. 2012 May;
12(13):2212-20.
PMID: 22623153
The CA 19-9 antigen is currently the best individual marker for the detection of pancreatic cancer. In order to optimize the CA 19-9 assay and to develop approaches to further...
37.
Partyka K, McDonald M, Maupin K, Brand R, Kwon R, Simeone D, et al.
J Proteome Res
. 2012 Mar;
11(5):2904-11.
PMID: 22439797
Significant efforts are underway to develop new biomarkers from pancreatic cyst fluid. Previous research has made use of cyst fluid collected from surgically removed cysts, but the clinical implementation of...
38.
Yue T, Maupin K, Fallon B, Li L, Partyka K, Anderson M, et al.
PLoS One
. 2012 Jan;
6(12):e29180.
PMID: 22220206
The CA 19-9 assay detects a carbohydrate antigen on multiple protein carriers, some of which may be preferential carriers of the antigen in cancer. We tested the hypothesis that the...
39.
Haab B, Yue T
Methods Mol Biol
. 2011 Sep;
785:223-36.
PMID: 21901603
The antibody-lectin sandwich arrays (ALSA) is a powerful new tool for glycoproteomics research. ALSA enables precise measurements of the glycosylation states of multiple proteins captured directly from biological samples. The...
40.
Maupin K, Liden D, Haab B
Glycobiology
. 2011 Aug;
22(1):160-9.
PMID: 21875884
Glycan-binding proteins are commonly used as analytical reagents to detect the levels of specific glycan structures in biological samples. A detailed knowledge of the specificities of glycan-binding proteins is required...