Kevin A Maupin
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Explore the profile of Kevin A Maupin including associated specialties, affiliations and a list of published articles.
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25
Citations
434
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Recent Articles
1.
Kulkarni H, Maupin K, Brennan T, Forsberg J, Rogers D, Olson M, et al.
J Nucl Med
. 2024 Sep;
65(11):1815.
PMID: 39237345
No abstract available.
2.
Maupin K, Diegel C, Stevens P, Dick D, Williams B
FEBS Open Bio
. 2022 Sep;
12(10):1717-1728.
PMID: 36062328
We previously observed that genomic loss of galectin-3 (Gal-3; encoded by Lgals3) in mice has a significant protective effect on age-related bone loss. Gal-3 has both intracellular and extracellular functionality,...
3.
Zamarioli A, Adam G, Maupin K, Childress P, Brinker A, Ximenez J, et al.
Front Endocrinol (Lausanne)
. 2022 Sep;
13:910901.
PMID: 36046782
Unloading associated with spaceflight results in bone loss and increased fracture risk. Bone morphogenetic protein 2 (BMP2) is known to enhance bone formation, in part, through molecular pathways associated with...
4.
Zamarioli A, Campbell Z, Maupin K, Childress P, Ximenez J, Adam G, et al.
NPJ Microgravity
. 2021 Mar;
7(1):12.
PMID: 33772025
With increased human presence in space, bone loss and fractures will occur. Thrombopoietin (TPO) is a recently patented bone healing agent. Here, we investigated the systemic effects of TPO on...
5.
Bhatti F, Dadwal U, Valuch C, Tewari N, Awosanya O, Staut C, et al.
Bone
. 2021 Feb;
146:115883.
PMID: 33581374
Angiogenesis is a vital process during the regeneration of bone tissue. The aim of this study was to investigate angiogenesis at the fracture site as well as at distal locations...
6.
Kanagasabapathy D, Blosser R, Maupin K, Hong J, Alvarez M, Ghosh J, et al.
Aging (Albany NY)
. 2020 Jul;
12(14):15121-15133.
PMID: 32634116
Megakaryocytes (MKs) support bone formation by stimulating osteoblasts (OBs) and inhibiting osteoclasts (OCs). Aging results in higher bone resorption, leading to bone loss. Whereas previous studies showed the effects of...
7.
Maupin K, Dick D, Lee J, Williams B
Calcif Tissue Int
. 2019 Nov;
106(3):283-293.
PMID: 31745588
Sex hormone deprivation commonly occurs following menopause in women or after androgen-depletion during prostate cancer therapy in men, resulting in rapid bone turnover and loss of bone mass. There is...
8.
Maupin K, Childress P, Brinker A, Khan F, Abeysekera I, Aguilar I, et al.
NPJ Microgravity
. 2019 Oct;
5:21.
PMID: 31583271
Gravity has an important role in both the development and maintenance of bone mass. This is most evident in the rapid and intense bone loss observed in both humans and...
9.
Dadwal U, Maupin K, Zamarioli A, Tucker A, Harris J, Fischer J, et al.
Sci Rep
. 2019 Aug;
9(1):11419.
PMID: 31388031
Spaceflight results in reduced mechanical loading of the skeleton, which leads to dramatic bone loss. Low bone mass is associated with increased fracture risk, and this combination may compromise future,...
10.
Maupin K, Himes E, Plett A, Chua H, Singh P, Ghosh J, et al.
Bone
. 2019 Jul;
127:452-459.
PMID: 31299382
Osteoblast number and activity decreases with aging, contributing to the age-associated decline of bone mass, but the mechanisms underlying changes in osteoblast activity are not well understood. Here, we show...