Belinda B Willard
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Explore the profile of Belinda B Willard including associated specialties, affiliations and a list of published articles.
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18
Citations
361
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Recent Articles
1.
Taye N, Karoulias S, Balic Z, Wang L, Willard B, Martin D, et al.
bioRxiv
. 2025 Feb;
PMID: 39896540
Weill-Marchesani syndrome (WMS) is characterized by severe short stature, short hands and feet (brachydactyly), joint contractures, tight skin, and heart valve, eye, and skin anomalies. Whereas recessive WMS is caused...
2.
Osborn L, Schultz K, Massey W, DeLucia B, Choucair I, Varadharajan V, et al.
Proc Natl Acad Sci U S A
. 2022 Nov;
119(48):e2202934119.
PMID: 36417437
The molecular mechanisms by which dietary fruits and vegetables confer cardiometabolic benefits remain poorly understood. Historically, these beneficial properties have been attributed to the antioxidant activity of flavonoids. Here, we...
3.
Hetz R, Magaway C, Everett J, Li L, Willard B, Freeze H, et al.
Biochem Biophys Res Commun
. 2022 Oct;
632:165-172.
PMID: 36209585
N-glycanase 1(NGLY1) catalyzes the removal of N-linked glycans from newly synthesized or misfolded protein. NGLY1 deficiency is a recently diagnosed rare genetic disorder. The affected individuals present a broad spectrum...
4.
Doh C, Dominic K, Swanberg C, Bharambe N, Willard B, Li L, et al.
ACS Omega
. 2022 May;
7(16):14189-14202.
PMID: 35573219
Cardiac myosin binding protein C (cMyBPC) is a critical multidomain protein that modulates myosin cross bridge behavior and cardiac contractility. cMyBPC is principally regulated by phosphorylation of the residues within...
5.
Singh V, Huang E, Pathak V, Willard B, Allende D, Nagy L
Hepatol Commun
. 2022 Apr;
6(8):2022-2041.
PMID: 35438255
Receptor-interaction protein kinase 3 (RIP3), a critical determinant of the necroptotic pathway of programmed cell death, contributes to injury in murine models of alcohol-associated liver disease (ALD); however, the underlying...
6.
Hetz R, Beeler E, Janoczkin A, Kiers S, Li L, Willard B, et al.
Front Nutr
. 2022 Jan;
8:765391.
PMID: 35096927
Inorganic phosphate (Pi) is an essential nutrient for the human body which exerts adverse health effects in excess and deficit. High Pi-mediated cytotoxicity has been shown to induce systemic organ...
7.
Osborn L, Orabi D, Goudzari M, Sangwan N, Banerjee R, Brown A, et al.
Immunometabolism
. 2021 Nov;
3(4).
PMID: 34804604
Background: A major contributor to cardiometabolic disease is caloric excess, often a result of consuming low cost, high calorie fast food. Studies have demonstrated the pivotal role of gut microbes...
8.
Welch N, Singh S, Kumar A, Dhruba S, Mishra S, Sekar J, et al.
J Biol Chem
. 2021 Aug;
297(3):101023.
PMID: 34343564
Ammonia is a cytotoxic molecule generated during normal cellular functions. Dysregulated ammonia metabolism, which is evident in many chronic diseases such as liver cirrhosis, heart failure, and chronic obstructive pulmonary...
9.
Rennison J, Li L, Lin C, Lovano B, Castel L, Wass S, et al.
Pflugers Arch
. 2021 Jan;
473(3):461-475.
PMID: 33454842
Atrial fibrillation (AF) is strongly associated with risk of stroke and heart failure. AF promotes atrial remodeling that increases risk of stroke due to left atrial thrombogenesis, and increases energy...
10.
Bulek K, Zhao J, Liao Y, Rana N, Corridoni D, Antanaviciute A, et al.
J Clin Invest
. 2020 Jun;
130(8):4218-4234.
PMID: 32597834
Gasdermin D (GSDMD) induces pyroptosis via the pore-forming activity of its N-terminal domain, cleaved by activated caspases associated with the release of IL-1β. Here, we report a nonpyroptotic role of...