Bach-Cuc Nguyen
Overview
Explore the profile of Bach-Cuc Nguyen including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
704
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Recent Articles
1.
Khan M, Frustino J, Villa A, Nguyen B, Woo S, Johnson W, et al.
Hum Genomics
. 2023 Aug;
17(1):72.
PMID: 37542347
Head and neck cancers are a complex malignancy comprising multiple anatomical sites, with cancer of the oral cavity ranking among the deadliest and the most disfiguring cancers globally. Oral cancer...
2.
Khan M, Frustino J, Villa A, Nguyen B, Woo S, Johnson W, et al.
bioRxiv
. 2023 Mar;
PMID: 36993637
Author Summary: Patients harboring oral premalignant lesions (PMLs) have an increased risk of developing oral squamous cell carcinoma (OSCC), but the underlying mechanisms driving transformation of PMLs to OSCC remain...
3.
Chandler K, Alamoud K, Stahl V, Nguyen B, Kartha V, Bais M, et al.
Mol Omics
. 2020 Mar;
16(3):195-209.
PMID: 32203567
Epidermal growth factor receptor (EGFR) is a major driver of head and neck cancer, a devastating malignancy with a major sub-site in the oral cavity manifesting as oral squamous cell...
4.
Kartha V, Alamoud K, Sadykov K, Nguyen B, Laroche F, Feng H, et al.
Genome Med
. 2018 Jul;
10(1):54.
PMID: 30029671
Background: Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy characterized by tumor heterogeneity, locoregional metastases, and resistance to existing treatments. Although a number of genomic and molecular...
5.
Restivo G, Nguyen B, Dziunycz P, Ristorcelli E, Ryan R, Yalcin Ozuysal O, et al.
EMBO J
. 2011 Sep;
30(22):4571-85.
PMID: 21909072
While the pro-differentiation and tumour suppressive functions of Notch signalling in keratinocytes are well established, the underlying mechanisms remain poorly understood. We report here that interferon regulatory factor 6 (IRF6),...
6.
Hu B, Lefort K, Qiu W, Nguyen B, Rajaram R, Castillo E, et al.
Genes Dev
. 2010 Jul;
24(14):1519-32.
PMID: 20634318
Epithelial-mesenchymal interactions are key to skin morphogenesis and homeostasis. We report that maintenance of the hair follicle keratinocyte cell fate is defective in mice with mesenchymal deletion of the CSL/RBP-Jkappa...
7.
Wu X, Nguyen B, Dziunycz P, Chang S, Brooks Y, Lefort K, et al.
Nature
. 2010 May;
465(7296):368-72.
PMID: 20485437
Calcineurin inhibitors such as cyclosporin A (CsA) are the mainstay of immunosuppressive treatment for organ transplant recipients. Squamous cell carcinoma (SCC) of the skin is a major complication of treatment...
8.
Thomason H, Zhou H, Kouwenhoven E, Dotto G, Restivo G, Nguyen B, et al.
J Clin Invest
. 2010 Apr;
120(5):1561-9.
PMID: 20424327
Cleft palate is a common congenital disorder that affects up to 1 in 2,500 live human births and results in considerable morbidity to affected individuals and their families. The etiology...
9.
Devgan V, Nguyen B, Oh H, Dotto G
J Biol Chem
. 2006 Aug;
281(41):30463-70.
PMID: 16912042
p21 plays a dual role in keratinocyte growth and differentiation control. It restricts the number of keratinocyte stem cell populations while inhibiting the later stages of differentiation independently of the...
10.
Nguyen B, Lefort K, Mandinova A, Antonini D, Devgan V, Della Gatta G, et al.
Genes Dev
. 2006 Apr;
20(8):1028-42.
PMID: 16618808
Notch signaling promotes commitment of keratinocytes to differentiation and suppresses tumorigenesis. p63, a p53 family member, has been implicated in establishment of the keratinocyte cell fate and/or maintenance of epithelial...