Arijit A Adhikari
Overview
Explore the profile of Arijit A Adhikari including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
364
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Fernandes S, Meyer S, Shah J, Adhikari A, Kerr W, Chisholm J
Molecules
. 2022 Dec;
27(23).
PMID: 36500543
Inhibition of phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP) with small molecule inhibitors leads to apoptosis in tumor cells. Inhibitors that target both SHIP1 and SHIP2 (pan-SHIP1/2 inhibitors) may have benefits in these...
2.
Li D, Chaudhari S, Lee Y, Sojoodi M, Adhikari A, Zukerberg L, et al.
Sci Adv
. 2022 Aug;
8(34):eabo2794.
PMID: 36026454
Altered host-microbe interactions and increased intestinal permeability have been implicated in disease pathogenesis. However, the mechanisms by which intestinal microbes affect epithelial barrier integrity remain unclear. Here, we investigate the...
3.
Yao L, DAgostino G, Park J, Hang S, Adhikari A, Zhang Y, et al.
Nat Microbiol
. 2022 Aug;
7(9):1404-1418.
PMID: 35982310
Members of the human gut microbiome enzymatically process many bioactive molecules in the gastrointestinal tract. Most gut bacterial modifications characterized so far are hydrolytic or reductive in nature. Here we...
4.
Adhikari A, Ramachandran D, Chaudhari S, Powell C, Li W, McCurry M, et al.
ACS Chem Biol
. 2021 Jul;
16(8):1401-1412.
PMID: 34279901
Bile acids play crucial roles in host physiology by acting both as detergents that aid in digestion and as signaling molecules that bind to host receptors. Gut bacterial bile salt...
5.
Chaudhari S, Luo J, Harris D, Aliakbarian H, Yao L, Paik D, et al.
Cell Host Microbe
. 2021 Jan;
29(3):408-424.e7.
PMID: 33434516
Bariatric surgery is the most effective treatment for type 2 diabetes and is associated with changes in gut metabolites. Previous work uncovered a gut-restricted TGR5 agonist with anti-diabetic properties-cholic acid-7-sulfate...
6.
Adhikari A, Seegar T, Ficarro S, McCurry M, Ramachandran D, Yao L, et al.
Nat Chem Biol
. 2020 Feb;
16(3):318-326.
PMID: 32042200
Bile salt hydrolase (BSH) enzymes are widely expressed by human gut bacteria and catalyze the gateway reaction leading to secondary bile acid formation. Bile acids regulate key metabolic and immune...
7.
Pedicone C, Fernandes S, Dungan O, Dormann S, Viernes D, Adhikari A, et al.
J Cell Sci
. 2019 Nov;
133(5).
PMID: 31780579
We show here that both SHIP1 () and its paralog SHIP2 (1) are expressed at protein level in microglia. To examine whether targeting of SHIP paralogs might influence microglial physiology...
8.
Suzuki T, Mate N, Adhikari A, Chisholm J
Molecules
. 2019 Nov;
24(22).
PMID: 31731742
2-Substituted indoles may be directly transformed to 3,3-dialkyl indolenines with trichloroacetimidate electrophiles and the Lewis acid TMSOTf. These reactions provide rapid access to complex indolenines which are present in a...
9.
Mahajani N, Meador R, Smith T, Canarelli S, Adhikari A, Shah J, et al.
J Org Chem
. 2019 May;
84(12):7871-7882.
PMID: 31117564
Trichloroacetimidates are useful reagents for the synthesis of esters under mild conditions that do not require an exogenous promoter. These conditions avoid the undesired decomposition of substrates with sensitive functional...
10.
Yao L, Seaton S, Ndousse-Fetter S, Adhikari A, DiBenedetto N, Mina A, et al.
Elife
. 2018 Jul;
7.
PMID: 30014852
The human gut microbiota impacts host metabolism and has been implicated in the pathophysiology of obesity and metabolic syndromes. However, defining the roles of specific microbial activities and metabolites on...