Snehal N Chaudhari
Overview
Explore the profile of Snehal N Chaudhari including associated specialties, affiliations and a list of published articles.
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17
Citations
481
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Recent Articles
1.
Chen Y, Chaudhari S, Harris D, Roberts C, Moscalu A, Mathur V, et al.
Cell Host Microbe
. 2024 Jul;
32(8):1315-1330.e5.
PMID: 39043190
Bariatric surgical procedures such as sleeve gastrectomy (SG) provide effective type 2 diabetes (T2D) remission in human patients. Previous work demonstrated that gastrointestinal levels of the bacterial metabolite lithocholic acid...
2.
DAgostino G, Chaudhari S, Devlin A
Nat Chem Biol
. 2024 Feb;
20(4):410-421.
PMID: 38347214
Recent studies have demonstrated that metabolites produced by commensal bacteria causally influence health and disease. The sulfated metabolome is one class of molecules that has recently come to the forefront...
3.
Meyer M, Bernal-Mizrachi C, Bikle D, Biyani M, Campbell M, Chaudhari S, et al.
J Steroid Biochem Mol Biol
. 2023 Jan;
228:106247.
PMID: 36639037
The 24th Workshop on Vitamin D was held September 7-9, 2022 in Austin, Texas and covered a wide diversity of research in the vitamin D field from across the globe....
4.
Li D, Chaudhari S, Lee Y, Sojoodi M, Adhikari A, Zukerberg L, et al.
Sci Adv
. 2022 Aug;
8(34):eabo2794.
PMID: 36026454
Altered host-microbe interactions and increased intestinal permeability have been implicated in disease pathogenesis. However, the mechanisms by which intestinal microbes affect epithelial barrier integrity remain unclear. Here, we investigate the...
5.
Chaudhari S, McCurry M, Devlin A
Nat Chem Biol
. 2021 Sep;
17(10):1046-1056.
PMID: 34552222
Human-associated microorganisms play a vital role in human health, and microbial imbalance has been linked to a wide range of disease states. In this Review, we explore recent efforts to...
6.
Adhikari A, Ramachandran D, Chaudhari S, Powell C, Li W, McCurry M, et al.
ACS Chem Biol
. 2021 Jul;
16(8):1401-1412.
PMID: 34279901
Bile acids play crucial roles in host physiology by acting both as detergents that aid in digestion and as signaling molecules that bind to host receptors. Gut bacterial bile salt...
7.
Chaudhari S, Devlin A
Bio Protoc
. 2021 Apr;
11(6).
PMID: 33855108
The activation of the Takeda G-protein receptor 5 (TGR5, also known as the G protein-coupled bile acid receptor 1, GPBAR1) in enteroendocrine L-cells results in secretion of the anti-diabetic hormone...
8.
Chaudhari S, Luo J, Harris D, Aliakbarian H, Yao L, Paik D, et al.
Cell Host Microbe
. 2021 Jan;
29(3):408-424.e7.
PMID: 33434516
Bariatric surgery is the most effective treatment for type 2 diabetes and is associated with changes in gut metabolites. Previous work uncovered a gut-restricted TGR5 agonist with anti-diabetic properties-cholic acid-7-sulfate...
9.
Chaudhari S, Harris D, Aliakbarian H, Luo J, Henke M, Subramaniam R, et al.
Nat Chem Biol
. 2020 Aug;
17(1):20-29.
PMID: 32747812
Bariatric surgery, the most effective treatment for obesity and type 2 diabetes, is associated with increased levels of the incretin hormone glucagon-like peptide-1 (GLP-1) and changes in levels of circulating...
10.
Adhikari A, Seegar T, Ficarro S, McCurry M, Ramachandran D, Yao L, et al.
Nat Chem Biol
. 2020 Feb;
16(3):318-326.
PMID: 32042200
Bile salt hydrolase (BSH) enzymes are widely expressed by human gut bacteria and catalyze the gateway reaction leading to secondary bile acid formation. Bile acids regulate key metabolic and immune...