Anzhelika Karjalainen
Overview
Explore the profile of Anzhelika Karjalainen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
5
Citations
39
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Karjalainen A, Witalisz-Siepracka A, Prchal-Murphy M, Martin D, Sternberg F, Krunic M, et al.
Cell Mol Life Sci
. 2025 Mar;
82(1):98.
PMID: 40025196
Tyrosine kinase 2 (TYK2) deficiency and loss or inhibition of kinase activity in men and mice leads to similar immune compromised phenotypes, predominantly through impairment of interferon (IFN) and interleukin...
2.
Becerra B, Wittibschlager S, Patel Z, Kutschat A, Delano J, Che E, et al.
bioRxiv
. 2024 Sep;
PMID: 39314441
CRISPR tiling screens have advanced the identification and characterization of regulatory sequences but are limited by low resolution arising from the indirect readout of editing via guide RNA sequencing. This...
3.
Fortelny N, Farlik M, Fife V, Gorki A, Lassnig C, Maurer B, et al.
Nat Immunol
. 2024 Apr;
25(5):847-859.
PMID: 38658806
Immune cells need to sustain a state of constant alertness over a lifetime. Yet, little is known about the regulatory processes that control the fluent and fragile balance that is...
4.
Karjalainen A, Shoebridge S, Krunic M, Simonovic N, Tebb G, Macho-Maschler S, et al.
Cancers (Basel)
. 2020 Jan;
12(1).
PMID: 31936322
We review the history of the tyrosine kinase 2 (TYK2) as the founding member of the Janus kinase (JAK) family and outline its structure-function relation. Gene-targeted mice and hereditary defects...
5.
Karjalainen A, Doan P, Chandraseelan J, Sandberg O, Yli-Harja O, Candeias N, et al.
Anticancer Agents Med Chem
. 2017 Mar;
17(12):1710-1720.
PMID: 28356015
Background: Phenolic compounds are known for their cytotoxic properties against cancer cells despite their still unclear general mechanism of action. Herein is reported the evaluation of the cytotoxic effects of...
6.
Synthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines
Doan P, Karjalainen A, Chandraseelan J, Sandberg O, Yli-Harja O, Rosholm T, et al.
Eur J Med Chem
. 2016 May;
120:296-303.
PMID: 27214140
Development of novel anticancer drugs is inevitable to improve treatment of cancers. In this study, novel derivatives of indoline and morpholine were synthesized and tested for their cytotoxic effects on...