Birgit Strobl
Overview
Explore the profile of Birgit Strobl including associated specialties, affiliations and a list of published articles.
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Articles
93
Citations
2916
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Recent Articles
1.
Karjalainen A, Witalisz-Siepracka A, Prchal-Murphy M, Martin D, Sternberg F, Krunic M, et al.
Cell Mol Life Sci
. 2025 Mar;
82(1):98.
PMID: 40025196
Tyrosine kinase 2 (TYK2) deficiency and loss or inhibition of kinase activity in men and mice leads to similar immune compromised phenotypes, predominantly through impairment of interferon (IFN) and interleukin...
2.
Miranda S, Lassnig C, Schmidhofer K, Kjartansdottir H, Vogl C, Tangermann S, et al.
Nat Commun
. 2024 Dec;
15(1):10493.
PMID: 39622833
Candida albicans is the most common human fungal pathogen, causing diseases ranging from local to life-threating systemic infections. Tyrosine kinase 2 (TYK2), a crucial mediator in several cytokine signaling pathways,...
3.
Babadei O, Strobl B, Muller M, Decker T
J Biol Chem
. 2024 Sep;
300(10):107771.
PMID: 39276937
Interferon-induced genes are among the best-studied groups of coregulated genes. Nevertheless, intense research into their regulation, supported by new technologies, is continuing to provide insights into their many layers of...
4.
Redmer T, Raigel M, Sternberg C, Ziegler R, Probst C, Lindner D, et al.
Mol Cancer
. 2024 May;
23(1):114.
PMID: 38811984
Background: Prostate cancer develops through malignant transformation of the prostate epithelium in a stepwise, mutation-driven process. Although activator protein-1 transcription factors such as JUN have been implicated as potential oncogenic...
5.
Fortelny N, Farlik M, Fife V, Gorki A, Lassnig C, Maurer B, et al.
Nat Immunol
. 2024 Apr;
25(5):847-859.
PMID: 38658806
Immune cells need to sustain a state of constant alertness over a lifetime. Yet, little is known about the regulatory processes that control the fluent and fragile balance that is...
6.
Granucci F, Marongiu L, Strobl B
Front Immunol
. 2023 Jul;
14:1234710.
PMID: 37497235
No abstract available.
7.
Sukhbaatar N, Scholler M, Fritsch S, Linke M, Horer S, Trager M, et al.
Blood
. 2023 Apr;
141(23):2878-2890.
PMID: 37018657
Iron is an essential cellular metal that is important for many physiological functions including erythropoiesis and host defense. It is absorbed from the diet in the duodenum and loaded onto...
8.
Moritsch S, Modl B, Scharf I, Janker L, Zwolanek D, Timelthaler G, et al.
Oncoimmunology
. 2022 Oct;
11(1):2127271.
PMID: 36185806
Janus kinase Tyk2 is implicated in cancer immune surveillance, but its role in solid tumors is not well defined. We used Tyk2 knockout mice (Tyk2) and mice with conditional deletion...
9.
Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling
Zahalka S, Starkl P, Watzenboeck M, Farhat A, Radhouani M, Deckert F, et al.
Mucosal Immunol
. 2022 Jul;
15(5):896-907.
PMID: 35856089
Environmental microbial triggers shape the development and functionality of the immune system. Alveolar macrophages (AMs), tissue-resident macrophages of the lungs, are in constant and direct contact with inhaled particles and...
10.
Woess K, Macho-Maschler S, Schenau D, Butler M, Lassnig C, Valcanover D, et al.
Haematologica
. 2022 Jan;
108(4):993-1005.
PMID: 35021603
Tyrosine kinase 2 (TYK2) is a member of the Janus kinase/signal transducer and activator of transcription pathway, which is central in cytokine signaling. Previously, germline TYK2 mutations have been described...