Caroline Lassnig
Overview
Explore the profile of Caroline Lassnig including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
1076
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0
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Recent Articles
1.
Karjalainen A, Witalisz-Siepracka A, Prchal-Murphy M, Martin D, Sternberg F, Krunic M, et al.
Cell Mol Life Sci
. 2025 Mar;
82(1):98.
PMID: 40025196
Tyrosine kinase 2 (TYK2) deficiency and loss or inhibition of kinase activity in men and mice leads to similar immune compromised phenotypes, predominantly through impairment of interferon (IFN) and interleukin...
2.
Miranda S, Lassnig C, Schmidhofer K, Kjartansdottir H, Vogl C, Tangermann S, et al.
Nat Commun
. 2024 Dec;
15(1):10493.
PMID: 39622833
Candida albicans is the most common human fungal pathogen, causing diseases ranging from local to life-threating systemic infections. Tyrosine kinase 2 (TYK2), a crucial mediator in several cytokine signaling pathways,...
3.
Fortelny N, Farlik M, Fife V, Gorki A, Lassnig C, Maurer B, et al.
Nat Immunol
. 2024 Apr;
25(5):847-859.
PMID: 38658806
Immune cells need to sustain a state of constant alertness over a lifetime. Yet, little is known about the regulatory processes that control the fluent and fragile balance that is...
4.
Schmidt U, Uluca B, Vokic I, Malik B, Kolbe T, Lassnig C, et al.
PLoS One
. 2023 Sep;
18(9):e0286256.
PMID: 37713409
FAM3C/ILEI is an important factor in epithelial-to-mesenchymal transition (EMT) induction, tumor progression and metastasis. Overexpressed in many cancers, elevated ILEI levels and secretion correlate with poor patient survival. Although ILEI's...
5.
Sukhbaatar N, Scholler M, Fritsch S, Linke M, Horer S, Trager M, et al.
Blood
. 2023 Apr;
141(23):2878-2890.
PMID: 37018657
Iron is an essential cellular metal that is important for many physiological functions including erythropoiesis and host defense. It is absorbed from the diet in the duodenum and loaded onto...
6.
Kolbe T, Lassnig C, Poelzl A, Palme R, Auer K, Rulicke T
Animals (Basel)
. 2022 Aug;
12(16).
PMID: 36009730
Ambient temperature is an important non-biotic environmental factor influencing immunological and oncological parameters in laboratory mice. It is under discussion which temperature is more appropriate and whether the commonly used...
7.
Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling
Zahalka S, Starkl P, Watzenboeck M, Farhat A, Radhouani M, Deckert F, et al.
Mucosal Immunol
. 2022 Jul;
15(5):896-907.
PMID: 35856089
Environmental microbial triggers shape the development and functionality of the immune system. Alveolar macrophages (AMs), tissue-resident macrophages of the lungs, are in constant and direct contact with inhaled particles and...
8.
Woess K, Macho-Maschler S, Schenau D, Butler M, Lassnig C, Valcanover D, et al.
Haematologica
. 2022 Jan;
108(4):993-1005.
PMID: 35021603
Tyrosine kinase 2 (TYK2) is a member of the Janus kinase/signal transducer and activator of transcription pathway, which is central in cytokine signaling. Previously, germline TYK2 mutations have been described...
9.
Demiroz D, Platanitis E, Bryant M, Fischer P, Prchal-Murphy M, Lercher A, et al.
PLoS Pathog
. 2021 Jul;
17(7):e1009697.
PMID: 34237114
Listeria monocytogenes (L. monocytogenes) is a food-borne bacterial pathogen. Innate immunity to L. monocytogenes is profoundly affected by type I interferons (IFN-I). Here we investigated host metabolism in L. monocytogenes-infected...
10.
Meissl K, Simonovic N, Amenitsch L, Witalisz-Siepracka A, Klein K, Lassnig C, et al.
Front Immunol
. 2020 Oct;
11:2189.
PMID: 33042133
Natural killer (NK) cells are important components of the innate immune defense against infections and cancers. Signal transducer and activator of transcription 1 (STAT1) is a transcription factor that is...