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Mathias Muller

Explore the profile of Mathias Muller including associated specialties, affiliations and a list of published articles. Areas
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Articles 184
Citations 6674
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Recent Articles
1.
Karjalainen A, Witalisz-Siepracka A, Prchal-Murphy M, Martin D, Sternberg F, Krunic M, et al.
Cell Mol Life Sci . 2025 Mar; 82(1):98. PMID: 40025196
Tyrosine kinase 2 (TYK2) deficiency and loss or inhibition of kinase activity in men and mice leads to similar immune compromised phenotypes, predominantly through impairment of interferon (IFN) and interleukin...
2.
Botrel L, Kreilinger A, Muller M, Pfeiffer M, Scheu V, Vowinkel N, et al.
Front Neurosci . 2025 Feb; 19:1476264. PMID: 40012677
In an EEG-based near real-time neurofeedback (NF) study in two parts using high immersive virtual reality (VR) we successfully trained healthy participants to downregulate their parietal alpha power, a neurophysiological...
3.
Miranda S, Lassnig C, Schmidhofer K, Kjartansdottir H, Vogl C, Tangermann S, et al.
Nat Commun . 2024 Dec; 15(1):10493. PMID: 39622833
Candida albicans is the most common human fungal pathogen, causing diseases ranging from local to life-threating systemic infections. Tyrosine kinase 2 (TYK2), a crucial mediator in several cytokine signaling pathways,...
4.
Babadei O, Strobl B, Muller M, Decker T
J Biol Chem . 2024 Sep; 300(10):107771. PMID: 39276937
Interferon-induced genes are among the best-studied groups of coregulated genes. Nevertheless, intense research into their regulation, supported by new technologies, is continuing to provide insights into their many layers of...
5.
Alesutan I, Razazian M, Luong T, Estepa M, Pitigala L, Henze L, et al.
Kidney Int . 2024 Jul; 106(4):611-624. PMID: 39084258
Medial vascular calcification in chronic kidney disease (CKD) involves pro-inflammatory pathways induced by hyperphosphatemia. Several interleukin 6 family members have been associated with pro-calcific effects in vascular smooth muscle cells...
6.
Fortelny N, Farlik M, Fife V, Gorki A, Lassnig C, Maurer B, et al.
Nat Immunol . 2024 Apr; 25(5):847-859. PMID: 38658806
Immune cells need to sustain a state of constant alertness over a lifetime. Yet, little is known about the regulatory processes that control the fluent and fragile balance that is...
7.
Ravi Sundar Jose Geetha A, Fischer K, Babadei O, Smesnik G, Vogt A, Platanitis E, et al.
EMBO J . 2024 Apr; 43(11):2233-2263. PMID: 38658796
Type I interferons (IFN-I, including IFNβ) and IFNγ produce overlapping, yet clearly distinct immunological activities. Recent data show that the distinctness of global transcriptional responses to the two IFN types...
8.
Suske T, Sorger H, Manhart G, Ruge F, Prutsch N, Zimmerman M, et al.
J Clin Invest . 2024 Apr; 134(8). PMID: 38618957
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive immature T cell cancer. Mutations in IL7R have been analyzed genetically, but downstream effector functions such as STAT5A and STAT5B hyperactivation...
9.
Wlassits R, Muller M, Fenzl K, Lamprecht T, Erlacher L
Open Access Rheumatol . 2024 Mar; 16:43-53. PMID: 38435420
Rheumatoid arthritis (RA) is a systemic, chronic, immune-mediated inflammatory condition. Treatments options encompass conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), biologic disease-modifying antirheumatic drugs (bDMARDs) like tumor necrosis factor (TNF) inhibitors...
10.
Schmidt U, Uluca B, Vokic I, Malik B, Kolbe T, Lassnig C, et al.
PLoS One . 2023 Sep; 18(9):e0286256. PMID: 37713409
FAM3C/ILEI is an important factor in epithelial-to-mesenchymal transition (EMT) induction, tumor progression and metastasis. Overexpressed in many cancers, elevated ILEI levels and secretion correlate with poor patient survival. Although ILEI's...