Angelique M Nelson
Overview
Explore the profile of Angelique M Nelson including associated specialties, affiliations and a list of published articles.
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19
Citations
1439
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Recent Articles
1.
Gregor B, Coston M, Adams E, Arakaki J, Borensztejn A, Do T, et al.
Nat Protoc
. 2023 Dec;
19(2):565-594.
PMID: 38087082
To produce abundant cell culture samples to generate large, standardized image datasets of human induced pluripotent stem (hiPS) cells, we developed an automated workflow on a Hamilton STAR liquid handler...
2.
Viana M, Chen J, Knijnenburg T, Vasan R, Yan C, Arakaki J, et al.
Nature
. 2023 Jan;
613(7943):345-354.
PMID: 36599983
Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviours...
3.
Grancharova T, Gerbin K, Rosenberg A, Roco C, Arakaki J, DeLizo C, et al.
Sci Rep
. 2021 Aug;
11(1):15845.
PMID: 34349150
We performed a comprehensive analysis of the transcriptional changes occurring during human induced pluripotent stem cell (hiPSC) differentiation to cardiomyocytes. Using single cell RNA-seq, we sequenced > 20,000 single cells...
4.
Gerbin K, Grancharova T, Donovan-Maiye R, Hendershott M, Anderson H, Brown J, et al.
Cell Syst
. 2021 May;
12(6):670-687.e10.
PMID: 34043964
Although some cell types may be defined anatomically or by physiological function, a rigorous definition of cell state remains elusive. Here, we develop a quantitative, imaging-based platform for the systematic...
5.
Yao Z, Mich J, Ku S, Menon V, Krostag A, Martinez R, et al.
Cell Stem Cell
. 2017 Jan;
20(1):120-134.
PMID: 28094016
During human brain development, multiple signaling pathways generate diverse cell types with varied regional identities. Here, we integrate single-cell RNA sequencing and clonal analyses to reveal lineage trees and molecular...
6.
Thomsen E, Mich J, Yao Z, Hodge R, Doyle A, Jang S, et al.
Nat Methods
. 2015 Nov;
13(1):87-93.
PMID: 26524239
The diverse progenitors that give rise to the human neocortex have been difficult to characterize because progenitors, particularly radial glia (RG), are rare and are defined by a combination of...
7.
Martinez R, Stein J, Krostag A, Nelson A, Marken J, Menon V, et al.
Nucleic Acids Res
. 2015 Mar;
43(10):e65.
PMID: 25765640
Isogenic pluripotent stem cells are critical tools for studying human neurological diseases by allowing one to study the effects of a mutation in a fixed genetic background. Of particular interest...
8.
Ware C, Nelson A, Mecham B, Hesson J, Zhou W, Jonlin E, et al.
Proc Natl Acad Sci U S A
. 2014 Mar;
111(12):4484-9.
PMID: 24623855
The naïve pluripotent state has been shown in mice to lead to broad and more robust developmental potential relative to primed mouse epiblast cells. The human naïve ES cell state...
9.
Vencio E, Nelson A, Cavanaugh C, Ware C, Milller D, Garcia J, et al.
Prostate
. 2012 Feb;
72(13):1453-63.
PMID: 22314551
Background: CD90(+) prostate cancer-associated (CP) stromal cells represent a diseased cell type found only in tumor tissue. They differ from their normal counterpart in gene expression and inductive signaling. Genetic...
10.
Snider L, Geng L, Lemmers R, Kyba M, Ware C, Nelson A, et al.
PLoS Genet
. 2010 Nov;
6(10):e1001181.
PMID: 21060811
Each unit of the D4Z4 macrosatellite repeat contains a retrotransposed gene encoding the DUX4 double-homeobox transcription factor. Facioscapulohumeral dystrophy (FSHD) is caused by deletion of a subset of the D4Z4...