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Calysta Yan

Explore the profile of Calysta Yan including associated specialties, affiliations and a list of published articles. Areas
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Citations 114
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Recent Articles
1.
Gregor B, Coston M, Adams E, Arakaki J, Borensztejn A, Do T, et al.
Nat Protoc . 2023 Dec; 19(2):565-594. PMID: 38087082
To produce abundant cell culture samples to generate large, standardized image datasets of human induced pluripotent stem (hiPS) cells, we developed an automated workflow on a Hamilton STAR liquid handler...
2.
Viana M, Chen J, Knijnenburg T, Vasan R, Yan C, Arakaki J, et al.
Nature . 2023 Jan; 613(7943):345-354. PMID: 36599983
Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviours...
3.
Donovan-Maiye R, Brown J, Chan C, Ding L, Yan C, Gaudreault N, et al.
PLoS Comput Biol . 2022 Jan; 18(1):e1009155. PMID: 35041651
We introduce a framework for end-to-end integrative modeling of 3D single-cell multi-channel fluorescent image data of diverse subcellular structures. We employ stacked conditional β-variational autoencoders to first learn a latent...
4.
Grancharova T, Gerbin K, Rosenberg A, Roco C, Arakaki J, DeLizo C, et al.
Sci Rep . 2021 Aug; 11(1):15845. PMID: 34349150
We performed a comprehensive analysis of the transcriptional changes occurring during human induced pluripotent stem cell (hiPSC) differentiation to cardiomyocytes. Using single cell RNA-seq, we sequenced > 20,000 single cells...
5.
Gerbin K, Grancharova T, Donovan-Maiye R, Hendershott M, Anderson H, Brown J, et al.
Cell Syst . 2021 May; 12(6):670-687.e10. PMID: 34043964
Although some cell types may be defined anatomically or by physiological function, a rigorous definition of cell state remains elusive. Here, we develop a quantitative, imaging-based platform for the systematic...
6.
Williams N, Rhodehamel M, Yan C, Smith A, Jiao A, Murry C, et al.
Biomaterials . 2020 Feb; 240:119856. PMID: 32105818
Tissue engineering aims to capture the structural and functional aspects of diverse tissue types in vitro. However, most approaches are limited in their ability to produce complex 3D geometries that...