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Melissa C Hendershott

Explore the profile of Melissa C Hendershott including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 214
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Recent Articles
1.
Dixon J, Frick C, Leveille C, Garrison P, Lee P, Mogre S, et al.
bioRxiv . 2024 Jul; PMID: 38979140
To investigate the fundamental question of how cellular variations arise across spatiotemporal scales in a population of identical healthy cells, we focused on nuclear growth in hiPS cell colonies as...
2.
Gregor B, Coston M, Adams E, Arakaki J, Borensztejn A, Do T, et al.
Nat Protoc . 2023 Dec; 19(2):565-594. PMID: 38087082
To produce abundant cell culture samples to generate large, standardized image datasets of human induced pluripotent stem (hiPS) cells, we developed an automated workflow on a Hamilton STAR liquid handler...
3.
Viana M, Chen J, Knijnenburg T, Vasan R, Yan C, Arakaki J, et al.
Nature . 2023 Jan; 613(7943):345-354. PMID: 36599983
Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviours...
4.
Gerbin K, Grancharova T, Donovan-Maiye R, Hendershott M, Anderson H, Brown J, et al.
Cell Syst . 2021 May; 12(6):670-687.e10. PMID: 34043964
Although some cell types may be defined anatomically or by physiological function, a rigorous definition of cell state remains elusive. Here, we develop a quantitative, imaging-based platform for the systematic...
5.
Roberts B, Hendershott M, Arakaki J, Gerbin K, Malik H, Nelson A, et al.
Stem Cell Reports . 2019 Apr; 12(5):1145-1158. PMID: 30956114
We describe a multistep method for endogenous tagging of transcriptionally silent genes in human induced pluripotent stem cells (hiPSCs). A monomeric EGFP (mEGFP) fusion tag and a constitutively expressed mCherry...
6.
Hendershott M, Vale R
Proc Natl Acad Sci U S A . 2014 Apr; 111(16):5860-5. PMID: 24706919
The microtubule (MT) cytoskeleton plays an essential role in mitosis, intracellular transport, cell shape, and cell migration. The assembly and disassembly of MTs, which can occur through the addition or...
7.
Graham J, Hendershott M, Terragni J, Cooper G
Mol Cell Biol . 2010 Sep; 30(22):5295-305. PMID: 20855526
Control of gene expression by the phosphatidylinositol (PI) 3-kinase/Akt pathway plays an important role in mammalian cell proliferation and survival, and numerous transcription factors and genes regulated by PI 3-kinase...
8.
Lieber S, Hendershott M, Pattanaporkratana A, Maclennan J
Phys Rev E Stat Nonlin Soft Matter Phys . 2007 Aug; 75(5 Pt 2):056308. PMID: 17677165
Multiple oil drops bouncing on the surface of a vertically vibrating bath of the same oil exhibit self-organization behavior in two dimensions [S. Protière, Y. Couder, E. Fort, and A....