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Andrey Anisimov

Explore the profile of Andrey Anisimov including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 2199
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Recent Articles
1.
Brouillard P, Murtomaki A, Leppanen V, Hyytiainen M, Mestre S, Potier L, et al.
J Clin Invest . 2024 May; 134(14). PMID: 38820174
Primary lymphedema (PL), characterized by tissue swelling, fat accumulation, and fibrosis, results from defects in lymphatic vessels or valves caused by mutations in genes involved in development, maturation, and function...
2.
Anisimov A, Fang S, Hemanthakumar K, Ord T, Van Avondt K, Chevre R, et al.
Nat Cardiovasc Res . 2023 Jul; 2(3):307-321. PMID: 37476204
Leukocytes and resident cells in the arterial wall contribute to atherosclerosis, especially at sites of disturbed blood flow. Expression of endothelial Tie1 receptor tyrosine kinase is enhanced at these sites,...
3.
Korhonen E, Murtomaki A, Kumar Jha S, Anisimov A, Pink A, Zhang Y, et al.
J Clin Invest . 2022 Jun; 132(15). PMID: 35763346
Vascular endothelial growth factor C (VEGF-C) induces lymphangiogenesis via VEGF receptor 3 (VEGFR3), which is encoded by the most frequently mutated gene in human primary lymphedema. Angiopoietins (Angs) and their...
4.
Muhl L, He L, Sun Y, Mae M, Pietila R, Liu J, et al.
Stem Cell Reports . 2022 Apr; 17(5):1089-1104. PMID: 35452595
Humanized mouse models and mouse-adapted SARS-CoV-2 virus are increasingly used to study COVID-19 pathogenesis, so it is important to learn where the SARS-CoV-2 receptor ACE2 is expressed. Here we mapped...
5.
Hemanthakumar K, Fang S, Anisimov A, Mayranpaa M, Mervaala E, Kivela R
Elife . 2021 Mar; 10. PMID: 33661096
Aging, obesity, hypertension, and physical inactivity are major risk factors for endothelial dysfunction and cardiovascular disease (CVD). We applied fluorescence-activated cell sorting (FACS), RNA sequencing, and bioinformatic methods to investigate...
6.
Lahde M, Heino S, Hogstrom J, Kaijalainen S, Anisimov A, Flanagan D, et al.
Gastroenterology . 2020 Sep; 160(1):245-259. PMID: 32941878
Background & Aims: Mutations in the APC gene and other genes in the Wnt signaling pathway contribute to development of colorectal carcinomas. R-spondins (RSPOs) are secreted proteins that amplify Wnt...
7.
Licht T, Kreisel T, Biala Y, Mohan S, Yaari Y, Anisimov A, et al.
J Neurosci . 2020 Jan; 40(5):974-995. PMID: 31959697
Multiple insults to the brain lead to neuronal cell death, thus raising the question to what extent can lost neurons be replenished by adult neurogenesis. Here we focused on the...
8.
Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin A, Auerbach R, et al.
Angiogenesis . 2018 May; 21(3):425-532. PMID: 29766399
The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions....
9.
Kareinen I, Baumann M, Nguyen S, Maaninka K, Anisimov A, Tozuka M, et al.
J Lipid Res . 2018 Mar; 59(6):945-957. PMID: 29581158
ApoA-I, the main structural and functional protein of HDL particles, is cardioprotective, but also highly sensitive to proteolytic cleavage. Here, we investigated the effect of cardiac mast cell activation and...
10.
Rademakers T, van der Vorst E, Daissormont I, Otten J, Theodorou K, Theelen T, et al.
Sci Rep . 2017 Mar; 7:45263. PMID: 28349940
During plaque progression, inflammatory cells progressively accumulate in the adventitia, paralleled by an increased presence of leaky vasa vasorum. We here show that next to vasa vasorum, also the adventitial...