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Andrey Anisimov

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Articles 42
Citations 2199
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Recent Articles
11.
Nikiforov V, Gao H, Zhou L, Anisimov A
Adv Exp Med Biol . 2016 Oct; 918:293-312. PMID: 27722868
Plague still poses a significant threat to human health and as a reemerging infection is unfamiliar to the majority of the modern medical doctors. In this chapter, the plague is...
12.
Raissadati A, Tuuminen R, Dashkevich A, Bry M, Kivela R, Anisimov A, et al.
Exp Clin Transplant . 2016 Sep; 15(2):203-212. PMID: 27588416
Objectives: Cardiac vascular endothelial growth factor-B transgene limits myocardial damage in rat infarction models. We investigated whether heart transplant vascular endothelial growth factor-B overexpression protected against ischemia-reperfusion injury. Materials And...
13.
Korhonen E, Lampinen A, Giri H, Anisimov A, Kim M, Allen B, et al.
J Clin Invest . 2016 Aug; 126(9):3495-510. PMID: 27548530
The angiopoietin/Tie (ANG/Tie) receptor system controls developmental and tumor angiogenesis, inflammatory vascular remodeling, and vessel leakage. ANG1 is a Tie2 agonist that promotes vascular stabilization in inflammation and sepsis, whereas...
14.
Bui H, Enis D, Robciuc M, Nurmi H, Cohen J, Chen M, et al.
J Clin Invest . 2016 May; 126(6):2167-80. PMID: 27159393
Lymphangiogenesis is supported by 2 homologous VEGFR3 ligands, VEGFC and VEGFD. VEGFC is required for lymphatic development, while VEGFD is not. VEGFC and VEGFD are proteolytically cleaved after cell secretion...
15.
Holopainen T, Rasanen M, Anisimov A, Tuomainen T, Zheng W, Tvorogov D, et al.
Proc Natl Acad Sci U S A . 2015 Oct; 112(42):13063-8. PMID: 26430242
Cardiac hypertrophy accompanies many forms of heart disease, including ischemic disease, hypertension, heart failure, and valvular disease, and it is a strong predictor of increased cardiovascular morbidity and mortality. Deletion...
16.
Marbacher S, Frosen J, Marjamaa J, Anisimov A, Honkanen P, von Gunten M, et al.
Stroke . 2014 Nov; 45(12):3684-90. PMID: 25370586
Background And Purpose: Aneurysm occlusion by intraluminal thrombus formation is the desired effect of all endovascular treatments. Intraluminal thrombus may, however, recanalize and be absorbed, unless it is infiltrated by...
17.
Jeltsch M, Kumar Jha S, Tvorogov D, Anisimov A, Leppanen V, Holopainen T, et al.
Circulation . 2014 Feb; 129(19):1962-71. PMID: 24552833
Background: Hennekam lymphangiectasia-lymphedema syndrome (Online Mendelian Inheritance in Man 235510) is a rare autosomal recessive disease, which is associated with mutations in the CCBE1 gene. Because of the striking phenotypic...
18.
Kivela R, Bry M, Robciuc M, Rasanen M, Taavitsainen M, Silvola J, et al.
EMBO Mol Med . 2014 Jan; 6(3):307-21. PMID: 24448490
Angiogenic growth factors have recently been linked to tissue metabolism. We have used genetic gain- and loss-of function models to elucidate the effects and mechanisms of action of vascular endothelial...
19.
DAmico G, Korhonen E, Anisimov A, Zarkada G, Holopainen T, Hagerling R, et al.
J Clin Invest . 2014 Jan; 124(2):824-34. PMID: 24430181
The endothelial Tie1 receptor is ligand-less, but interacts with the Tie2 receptor for angiopoietins (Angpt). Angpt2 is expressed in tumor blood vessels, and its blockade inhibits tumor angiogenesis. Here we...
20.
Yao L, Testini C, Tvorogov D, Anisimov A, Vargas S, Baluk P, et al.
Circ Res . 2014 Jan; 114(5):806-22. PMID: 24429550
Rationale: Lymphatic vessels in the respiratory tract normally mature into a functional network during the neonatal period, but under some pathological conditions they can grow as enlarged, dilated sacs that...