Amitesh Anand
Overview
Explore the profile of Amitesh Anand including associated specialties, affiliations and a list of published articles.
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24
Citations
373
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Recent Articles
1.
Patil A, Shirsath A, Anand A
iScience
. 2025 Jan;
27(12):111498.
PMID: 39759019
The development of a system to leverage molecular oxygen for energy-efficient pathways required several molecular adaptations. The enzymatic reduction of dioxygen to water is one such prominent evolutionary molecular trait....
2.
Srivastav S, Biswas A, Anand A
J Biol Chem
. 2024 Dec;
301(1):108052.
PMID: 39662826
The human body is an intricate ensemble of prokaryotic and eukaryotic cells, and this coexistence relies on the interplay of many biotic and abiotic factors. The inhabiting microbial population has...
3.
Poddar K, Anand A
J Vis Exp
. 2024 Jul;
(209).
PMID: 39072629
Many bacteria thrive in intricate natural communities, exhibiting key attributes of multicellularity such as communication, cooperation, and competition. The most prevalent manifestation of bacterial multicellular behavior is the formation of...
4.
Goel N, Srivastav S, Patel A, Shirsath A, Panda T, Patra M, et al.
Microbiol Spectr
. 2023 Oct;
11(6):e0222523.
PMID: 37855642
Energy generation pathways are a potential avenue for the development of novel antibiotics. However, bacteria possess remarkable resilience due to the compensatory pathways, which presents a challenge in this direction....
5.
Rychel K, Tan J, Patel A, Lamoureux C, Hefner Y, Szubin R, et al.
Cell Rep
. 2023 Sep;
42(9):113105.
PMID: 37713311
Relationships between the genome, transcriptome, and metabolome underlie all evolved phenotypes. However, it has proved difficult to elucidate these relationships because of the high number of variables measured. A recently...
6.
Vasudevan N, Motiwala Z, Ramesh R, Wagh S, Shingare R, Katte R, et al.
Eur J Med Chem
. 2023 Jul;
259:115633.
PMID: 37524010
Growing global demand for new molecules to treat tuberculosis has created an urgent need to develop novel strategies to combat the menace. BM212 related compounds were found to be potent...
7.
Anand A, Patel A, Chen K, Olson C, Phaneuf P, Lamoureux C, et al.
Nat Commun
. 2022 Jun;
13(1):3682.
PMID: 35760776
The bacterial respiratory electron transport system (ETS) is branched to allow condition-specific modulation of energy metabolism. There is a detailed understanding of the structural and biochemical features of respiratory enzymes;...
8.
Sastry A, Dillon N, Anand A, Poudel S, Hefner Y, Xu S, et al.
mSphere
. 2021 Aug;
6(4):e0044321.
PMID: 34431696
antibiotic susceptibility testing often fails to accurately predict drug efficacies, in part due to differences in the molecular composition between standardized bacteriologic media and physiological environments within the body. Here,...
9.
Machado H, Seif Y, Sakoulas G, Olson C, Hefner Y, Anand A, et al.
Commun Biol
. 2021 Jun;
4(1):793.
PMID: 34172889
While microbiological resistance to vancomycin in Staphylococcus aureus is rare, clinical vancomycin treatment failures are common, and methicillin-resistant S. aureus (MRSA) strains isolated from patients after prolonged vancomycin treatment failure...
10.
Anand A, Olson C, Sastry A, Patel A, Szubin R, Yang L, et al.
Cell Rep
. 2021 Apr;
35(1):108961.
PMID: 33826886
Pyruvate dehydrogenase complex (PDC) functions as the main determinant of the respiro-fermentative balance because it converts pyruvate to acetyl-coenzyme A (CoA), which then enters the TCA (tricarboxylic acid cycle). PDC...