Adam M Feist
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Explore the profile of Adam M Feist including associated specialties, affiliations and a list of published articles.
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112
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6456
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Recent Articles
1.
Alter T, Pieters P, Lloyd C, Feist A, Ozdemir E, Palsson B, et al.
Metab Eng Commun
. 2025 Mar;
20:e00257.
PMID: 40070513
Whole-cell biocatalysis facilitates the production of a wide range of industrially and pharmaceutically relevant molecules from sustainable feedstocks such as plastic wastes, carbon dioxide, lignocellulose, or plant-based sugar sources. The...
2.
Werner A, Avina Y, Johnsen J, Bratti F, Alt H, Mohamed E, et al.
Metab Eng
. 2024 Dec;
88:196-205.
PMID: 39701409
Poly (ethylene terephthalate) (PET) is one of the most ubiquitous plastics and can be depolymerized through biological and chemo-catalytic routes to its constituent monomers, terephthalic acid (TPA) and ethylene glycol...
3.
Dalldorf C, Hefner Y, Szubin R, Johnsen J, Mohamed E, Li G, et al.
Mol Biol Evol
. 2024 Nov;
41(11).
PMID: 39531644
The transcriptional regulatory network (TRN) in bacteria is thought to rapidly evolve in response to selection pressures, modulating transcription factor (TF) activities and interactions. In order to probe the limits...
4.
Champie A, Lachance J, Sastry A, Matteau D, Lloyd C, Grenier F, et al.
mBio
. 2024 Aug;
15(10):e0087324.
PMID: 39207109
Importance: Genomic streamlining can be employed in model organisms to reduce complexity and enhance strain predictability. One of the most striking examples is the bacterial strain DGF-298, notable for having...
5.
Munkler L, Mohamed E, Vazquez-Uribe R, Visby Nissen V, Rugbjerg P, Worberg A, et al.
Metab Eng
. 2024 Aug;
85:159-166.
PMID: 39111565
Advanced microbiome therapeutics have emerged as a powerful approach for the treatment of numerous diseases. While the genetic instability of genetically engineered microorganisms is a well-known challenge in the scale-up...
6.
Bleem A, Kuatsjah E, Johnsen J, Mohamed E, Alexander W, Kellermyer Z, et al.
Metab Eng
. 2024 Jun;
84:145-157.
PMID: 38936762
Biological conversion of lignin from biomass offers a promising strategy for sustainable production of fuels and chemicals. However, aromatic compounds derived from lignin commonly contain methoxy groups, and O-demethylation of...
7.
Kim H, Noh M, White E, Kandefer M, Wright A, Datta D, et al.
Nat Commun
. 2024 Apr;
15(1):3338.
PMID: 38688899
The field of hybrid engineered living materials seeks to pair living organisms with synthetic materials to generate biocomposite materials with augmented function since living systems can provide highly-programmable and complex...
8.
Choe D, Olson C, Szubin R, Yang H, Sung J, Feist A, et al.
Nat Commun
. 2024 Mar;
15(1):2356.
PMID: 38490991
Machine learning applied to large compendia of transcriptomic data has enabled the decomposition of bacterial transcriptomes to identify independently modulated sets of genes, such iModulons represent specific cellular functions. The...
9.
Goel N, Srivastav S, Patel A, Shirsath A, Panda T, Patra M, et al.
Microbiol Spectr
. 2023 Oct;
11(6):e0222523.
PMID: 37855642
Energy generation pathways are a potential avenue for the development of novel antibiotics. However, bacteria possess remarkable resilience due to the compensatory pathways, which presents a challenge in this direction....
10.
Rychel K, Tan J, Patel A, Lamoureux C, Hefner Y, Szubin R, et al.
Cell Rep
. 2023 Sep;
42(9):113105.
PMID: 37713311
Relationships between the genome, transcriptome, and metabolome underlie all evolved phenotypes. However, it has proved difficult to elucidate these relationships because of the high number of variables measured. A recently...