Alexander Zholos
Overview
Explore the profile of Alexander Zholos including associated specialties, affiliations and a list of published articles.
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12
Citations
351
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Recent Articles
1.
Soloviev A, Ivanova I, Sydorenko V, Sukhanova K, Melnyk M, Dryn D, et al.
Acta Physiol (Oxf)
. 2023 Jan;
237(3):e13922.
PMID: 36599422
Aim: Gold nanoparticles are widely used for biomedical applications, but the precise molecular mechanism of their interaction with cellular structures is still unclear. Assuming that intracellular calcium fluctuations associated with...
2.
Dryn D, Melnyk M, Kizub I, Hu H, Soloviev A, Zholos A
Fiziol Zh (1994)
. 2018 Mar;
62(2):79-86.
PMID: 29537229
The aim of our study was to investigate the role of mechanosensitive TRPV4 channels in the regulation of rat pulmonary artery smooth muscle (PASM) contractile activity induced by the activation...
3.
Dryn D, Luo J, Melnyk M, Zholos A, Hu H
Eur J Pharmacol
. 2017 Dec;
820:39-44.
PMID: 29198958
Gastrointestinal tract motility may be demoted significantly after surgery operations at least in part due to anaesthetic agents, but there is no comprehensive explanation of the molecular mechanism(s) of such...
4.
Soloviev A, Zholos A, Ivanova I, Novokhatska T, Tishkin S, Raevska A, et al.
Vascul Pharmacol
. 2015 Jun;
72:190-6.
PMID: 26044181
Colloidal gold nanoparticles (AuNPs) of ~5nm core size and Zeta-potential of -35mV, having absorption maximum and plasmon resonance in the range of 510-570nm, were studied as a potential K(+)-channel opener...
5.
McGarvey L, Butler C, Stokesberry S, Polley L, McQuaid S, Abdullah H, et al.
J Allergy Clin Immunol
. 2013 Nov;
133(3):704-12.e4.
PMID: 24210884
Background: The airway epithelium is exposed to a range of physical and chemical irritants in the environment that are known to trigger asthma. Transient receptor potential (TRP) cation channels play...
6.
Bidaux G, Beck B, Zholos A, Gordienko D, Lemonnier L, Flourakis M, et al.
J Biol Chem
. 2011 Dec;
287(5):2948-62.
PMID: 22128173
One important mechanism of the regulation of membrane ion channels involves their nonfunctional isoforms generated by alternative splicing. However, knowledge of such isoforms for the members of the transient receptor...
7.
Zholos A, Johnson C, Burdyga T, Melanaphy D
Adv Exp Med Biol
. 2011 Feb;
704:707-29.
PMID: 21290323
Recent studies show that mammalian melastatin TRPM nonselective cation channels (TRPM1-8), members of the largest and most diverse TRP subfamily, are widely expressed in the endothelium and vascular smooth muscles....
8.
Zholos A
Br J Pharmacol
. 2010 Mar;
159(8):1559-71.
PMID: 20233227
Mammalian transient receptor potential melastatin (TRPM) non-selective cation channels, the largest TRP subfamily, are widely expressed in excitable and non-excitable cells where they perform diverse functions ranging from detection of...
9.
Bidaux G, Flourakis M, Thebault S, Zholos A, Beck B, Gkika D, et al.
J Clin Invest
. 2007 May;
117(6):1647-57.
PMID: 17510704
In recent years, the transient receptor potential melastatin member 8 (TRPM8) channel has emerged as a promising prognostic marker and putative therapeutic target in prostate cancer (PCa). However, the mechanisms...
10.
Vanden Abeele F, Zholos A, Bidaux G, Shuba Y, Thebault S, Beck B, et al.
J Biol Chem
. 2006 Nov;
281(52):40174-82.
PMID: 17082190
TRPM8 represents an ion channel activated by cold temperatures and cooling agents, such as menthol, that underlies the cold-induced excitation of sensory neurons. Interestingly, the only human tissue outside the...