Alex L Nigg
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Explore the profile of Alex L Nigg including associated specialties, affiliations and a list of published articles.
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21
Citations
683
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Recent Articles
1.
Yavuz S, Kabbech H, van Staalduinen J, Linder S, van Cappellen W, Nigg A, et al.
Nucleic Acids Res
. 2023 Oct;
51(20):10992-11009.
PMID: 37791849
A wide range of nuclear proteins are involved in the spatio-temporal organization of the genome through diverse biological processes such as gene transcription and DNA replication. Upon stimulation by testosterone...
2.
Stabile R, Cabezas M, Verhagen M, Tucci F, van den Bosch T, De Herdt M, et al.
Cell Death Dis
. 2023 May;
14(5):337.
PMID: 37217493
Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1; also known as deleted in oral cancer or DOC1) is a tumor suppressor gene known to play functional roles in both cell cycle regulation...
3.
Identifying Molecular Changes in Early Cervical Cancer Samples of Patients That Developed Metastasis
de Geus V, Ewing-Graham P, de Koning W, de Koning M, van den Bosch T, Nigg A, et al.
Front Oncol
. 2022 Jan;
11:715077.
PMID: 35087740
Cervical cancer is one of the most common cancers in women worldwide. Patients diagnosed with early-stage cervical cancer have a good prognosis, however, 10-20% suffer from local or distant recurrent...
4.
Legerstee K, Abraham T, van Cappellen W, Nigg A, Slotman J, Houtsmuller A
Sci Rep
. 2021 Jan;
11(1):2315.
PMID: 33504939
Focal adhesions (FAs) are flat elongated structures that mediate cell migration and link the cytoskeleton to the extracellular matrix. Along the vertical axis FAs were shown to be composed of...
5.
van der Zwan M, Baan C, Colvin R, Smith R, White R, Ndishabandi D, et al.
Transplant Direct
. 2019 Jan;
5(1):e418.
PMID: 30656216
Background: Belatacept-based therapy in kidney transplant recipient has been shown to increase long-term renal allograft and patient survival compared with calcineurin inhibitor-based therapy, however, with an increased risk of acute...
6.
Sideras K, Galjart B, Vasaturo A, Pedroza-Gonzalez A, Biermann K, Mancham S, et al.
J Surg Oncol
. 2018 Jun;
118(1):68-76.
PMID: 29878369
Background And Objectives: Patients with isolated colorectal-cancer-liver-metastases (CRCLM) frequently undergo metastatectomy. Tumor-infiltrating-lymphocytes (TILs) have prognostic potential in the setting of primary colorectal cancer, however, their role in CRCLM is less...
7.
Gornati S, Schafer C, Eelkman Rooda O, Nigg A, De Zeeuw C, Hoebeek F
Cell Rep
. 2018 May;
23(9):2690-2704.
PMID: 29847799
The cerebellum plays a role in coordination of movements and non-motor functions. Cerebellar nuclei (CN) axons connect to various parts of the thalamo-cortical network, but detailed information on the characteristics...
8.
Mustafa D, Pedrosa R, Smid M, van der Weiden M, de Weerd V, Nigg A, et al.
Acta Neuropathol
. 2018 Jan;
135(4):581-599.
PMID: 29350274
The discovery of genes and molecular pathways involved in the formation of brain metastasis would direct the development of therapeutic strategies to prevent this deadly complication of cancer. By comparing...
9.
Herzog E, Eggink A, Reijnierse A, Kerkhof M, de Krijger R, Roks A, et al.
Placenta
. 2016 Dec;
49:72-79.
PMID: 28012458
Introduction: Offspring exposed to preeclampsia (PE) show an increased risk of cardiovascular disease in adulthood. We hypothesize that this is mediated by a disturbed vascular development of the placenta, umbilical...
10.
Sepe S, Milanese C, Gabriels S, Derks K, Payan-Gomez C, van IJcken W, et al.
Cell Rep
. 2016 May;
15(9):1866-75.
PMID: 27210754
The underlying relation between Parkinson's disease (PD) etiopathology and its major risk factor, aging, is largely unknown. In light of the causative link between genome stability and aging, we investigate...