Johan A Slotman
Overview
Explore the profile of Johan A Slotman including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
593
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Recent Articles
1.
Oukrich S, Hong J, Leon-Grooters M, van Cappellen W, Slotman J, Koenderink G, et al.
Biofilm
. 2025 Mar;
9:100261.
PMID: 40034339
The single most common microbe causing cardiovascular infections is (). produces coagulase that converts fibrinogen to fibrin, which is incorporated into biofilms. This process aids in adherence to intravascular structures,...
2.
Rajicic A, Giannini L, Gerrits E, van Buuren R, Melhem S, Slotman J, et al.
Glia
. 2024 Dec;
PMID: 39705191
A subpopulation of astrocytes expressing WD Repeat Domain 49 (WDR49) was recently identified in frontotemporal lobar degeneration (FTLD) with GRN pathogenic variants. This is the first study to investigate their...
3.
Rao S, Romal S, Torenvliet B, Slotman J, Huijs T, Mahmoudi T
Heliyon
. 2024 May;
10(10):e30740.
PMID: 38770342
Malaria, a major public health burden, is caused by spp parasites that first replicate in the human liver to establish infection before spreading to erythrocytes. Liver-stage malaria research has remained...
4.
Pascual-Garcia M, Unkel M, Slotman J, Bolleboom A, Bouwen B, Houtsmuller A, et al.
Cereb Cortex
. 2024 Apr;
34(4).
PMID: 38610088
The axons of neocortical pyramidal neurons are frequently myelinated. Heterogeneity in the topography of axonal myelination in the cerebral cortex has been attributed to a combination of electrophysiological activity, axonal...
5.
Yavuz S, Kabbech H, van Staalduinen J, Linder S, van Cappellen W, Nigg A, et al.
Nucleic Acids Res
. 2023 Oct;
51(20):10992-11009.
PMID: 37791849
A wide range of nuclear proteins are involved in the spatio-temporal organization of the genome through diverse biological processes such as gene transcription and DNA replication. Upon stimulation by testosterone...
6.
Verkerk A, Andrei D, Vermeer M, Kramer D, Schouten M, Arp P, et al.
J Invest Dermatol
. 2023 Sep;
144(2):284-295.e16.
PMID: 37716648
Desmosomes are dynamic complex protein structures involved in cellular adhesion. Disruption of these structures by loss-of-function variants in desmosomal genes leads to a variety of skin- and heart-related phenotypes. In...
7.
Koornneef L, Paul M, Houtsmuller A, Baarends W, Slotman J
Bio Protoc
. 2023 Jul;
13(14):e4780.
PMID: 37497444
During the first meiotic prophase in mouse, repair of SPO11-induced DNA double-strand breaks (DSBs), facilitating homologous chromosome synapsis, is essential to successfully complete the first meiotic cell division. Recombinases RAD51...
8.
Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability
Gaggioli V, Lo C, Reveron-Gomez N, Jasencakova Z, Domenech H, Nguyen H, et al.
Nat Cell Biol
. 2023 Jul;
25(7):1017-1032.
PMID: 37414849
Chromatin is dynamically reorganized when DNA replication forks are challenged. However, the process of epigenetic reorganization and its implication for fork stability is poorly understood. Here we discover a checkpoint-regulated...
9.
Swinkels M, Hordijk S, Burgisser P, Slotman J, Carter T, Leebeek F, et al.
J Thromb Haemost
. 2023 Apr;
21(7):1967-1980.
PMID: 37061132
Background: Von Willebrand factor (VWF) and VWF propeptide (VWFpp) are stored in eccentric nanodomains within platelet alpha-granules. VWF and VWFpp can undergo differential secretion following Weibel-Palade body exocytosis in endothelial...
10.
Smits D, Schot R, Krusy N, Wiegmann K, Utermohlen O, Mulder M, et al.
Brain
. 2023 Feb;
146(8):3528-3541.
PMID: 36732302
Biallelic loss-of-function variants in SMPD4 cause a rare and severe neurodevelopmental disorder with progressive congenital microcephaly and early death. SMPD4 encodes a sphingomyelinase that hydrolyses sphingomyelin into ceramide at neutral...