Tsion E Abraham
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Explore the profile of Tsion E Abraham including associated specialties, affiliations and a list of published articles.
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13
Citations
377
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Recent Articles
1.
Yavuz S, Abraham T, Houtsmuller A, van Royen M
Cells
. 2024 Oct;
13(20.
PMID: 39451211
The androgen receptor (AR), a member of the nuclear steroid hormone receptor family of transcription factors, plays a crucial role not only in the development of the male phenotype but...
2.
Yavuz S, Kabbech H, van Staalduinen J, Linder S, van Cappellen W, Nigg A, et al.
Nucleic Acids Res
. 2023 Oct;
51(20):10992-11009.
PMID: 37791849
A wide range of nuclear proteins are involved in the spatio-temporal organization of the genome through diverse biological processes such as gene transcription and DNA replication. Upon stimulation by testosterone...
3.
Legerstee K, Sueters J, Abraham T, Slotman J, Kremers G, Hoogenboom J, et al.
Biol Open
. 2022 Nov;
11(11).
PMID: 36409550
Focal adhesions (FAs) are the main cellular structures to link the intracellular cytoskeleton to the extracellular matrix. FAs mediate cell adhesion, are important for cell migration and are involved in...
4.
Ozgun F, Kaya Z, Morova T, Geverts B, Abraham T, Houtsmuller A, et al.
J Cell Sci
. 2021 Jul;
134(14).
PMID: 34318896
Androgen receptor (AR) splice variants are proposed to be a potential driver of lethal castration-resistant prostate cancer. AR splice variant 7 (ARv7) is the most commonly observed isoform and strongly...
5.
Legerstee K, Abraham T, van Cappellen W, Nigg A, Slotman J, Houtsmuller A
Sci Rep
. 2021 Jan;
11(1):2315.
PMID: 33504939
Focal adhesions (FAs) are flat elongated structures that mediate cell migration and link the cytoskeleton to the extracellular matrix. Along the vertical axis FAs were shown to be composed of...
6.
Comparison of High- and Low-LET Radiation-Induced DNA Double-Strand Break Processing in Living Cells
Roobol S, van den Bent I, van Cappellen W, Abraham T, Paul M, Kanaar R, et al.
Int J Mol Sci
. 2020 Sep;
21(18).
PMID: 32917044
High-linear-energy-transfer (LET) radiation is more lethal than similar doses of low-LET radiation types, probably a result of the condensed energy deposition pattern of high-LET radiation. Here, we compare high-LET α-particle...
7.
Roobol S, Hartjes T, Slotman J, de Kruijff R, Torrelo G, Abraham T, et al.
Nanotheranostics
. 2020 Jan;
4(1):14-25.
PMID: 31911891
Polymersomes have the potential to be applied in targeted alpha radionuclide therapy, while in addition preventing release of recoiling daughter isotopes. In this study, we investigated the cellular uptake, post...
8.
Roell D, Rosler T, Hessenkemper W, Kraft F, Hauschild M, Bartsch S, et al.
J Steroid Biochem Mol Biol
. 2019 Jan;
188:59-70.
PMID: 30615932
Androgen receptor (AR) antagonists are used for hormone therapy of prostate cancer (PCa). However resistance to the treatment occurs eventually. One possible reason is the occurrence of AR mutations that...
9.
Hoppenbrouwers T, Sultan A, Abraham T, Lemmens-den Toom N, Hansenova Manaskova S, van Cappellen W, et al.
Front Immunol
. 2018 Feb;
9:165.
PMID: 29459871
are strong inducers of neutrophil extracellular traps (NETs), a defense mechanism of neutrophils against pathogens. Our aim was to explore the role of Protein A in -induced NETosis. We determined...
10.
Hoppenbrouwers T, Autar A, Sultan A, Abraham T, van Cappellen W, Houtsmuller A, et al.
PLoS One
. 2017 May;
12(5):e0176472.
PMID: 28486563
Background: Multiple inducers of in vitro Neutrophil Extracellular Trap (NET) formation (NETosis) have been described. Since there is much variation in study design and results, our aim was to create...