Adriaan B Houtsmuller
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Explore the profile of Adriaan B Houtsmuller including associated specialties, affiliations and a list of published articles.
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115
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4759
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Recent Articles
1.
Komar Z, Verkaik N, Dahmani A, Montaudon E, Kanaar R, Houtsmuller A, et al.
NPJ Breast Cancer
. 2025 Feb;
11(1):17.
PMID: 39962055
Breast cancer is the most common cancer amongst women worldwide, however clinically validated chemotherapy response biomarkers that can accurately predict treatment response in patients are largely lacking. Therefore, in this...
2.
Yavuz S, Abraham T, Houtsmuller A, van Royen M
Cells
. 2024 Oct;
13(20.
PMID: 39451211
The androgen receptor (AR), a member of the nuclear steroid hormone receptor family of transcription factors, plays a crucial role not only in the development of the male phenotype but...
3.
Pascual-Garcia M, Unkel M, Slotman J, Bolleboom A, Bouwen B, Houtsmuller A, et al.
Cereb Cortex
. 2024 Apr;
34(4).
PMID: 38610088
The axons of neocortical pyramidal neurons are frequently myelinated. Heterogeneity in the topography of axonal myelination in the cerebral cortex has been attributed to a combination of electrophysiological activity, axonal...
4.
Yavuz S, Kabbech H, van Staalduinen J, Linder S, van Cappellen W, Nigg A, et al.
Nucleic Acids Res
. 2023 Oct;
51(20):10992-11009.
PMID: 37791849
A wide range of nuclear proteins are involved in the spatio-temporal organization of the genome through diverse biological processes such as gene transcription and DNA replication. Upon stimulation by testosterone...
5.
Koornneef L, Paul M, Houtsmuller A, Baarends W, Slotman J
Bio Protoc
. 2023 Jul;
13(14):e4780.
PMID: 37497444
During the first meiotic prophase in mouse, repair of SPO11-induced DNA double-strand breaks (DSBs), facilitating homologous chromosome synapsis, is essential to successfully complete the first meiotic cell division. Recombinases RAD51...
6.
Mayayo-Peralta I, Gregoricchio S, Schuurman K, Yavuz S, Zaalberg A, Kojic A, et al.
Nucleic Acids Res
. 2023 Apr;
51(18):9576-9593.
PMID: 37070193
How steroid hormone receptors (SHRs) regulate transcriptional activity remains partly understood. Upon activation, SHRs bind the genome together with a co-regulator repertoire, crucial to induce gene expression. However, it remains...
7.
Hari S, Slotman J, Vos Y, Floris C, van Cappellen W, Hagen C, et al.
Sci Rep
. 2022 Nov;
12(1):20185.
PMID: 36418420
Super-resolution fluorescence microscopy can be achieved by image reconstruction after spatially patterned illumination or sequential photo-switching and read-out. Reconstruction algorithms and microscope performance are typically tested using simulated image data,...
8.
Legerstee K, Sueters J, Abraham T, Slotman J, Kremers G, Hoogenboom J, et al.
Biol Open
. 2022 Nov;
11(11).
PMID: 36409550
Focal adhesions (FAs) are the main cellular structures to link the intracellular cytoskeleton to the extracellular matrix. FAs mediate cell adhesion, are important for cell migration and are involved in...
9.
Koornneef L, Slotman J, Sleddens-Linkels E, van Cappellen W, Barchi M, Toth A, et al.
PLoS Genet
. 2022 Jul;
18(7):e1010046.
PMID: 35857787
Recombinases RAD51 and its meiosis-specific paralog DMC1 accumulate on single-stranded DNA (ssDNA) of programmed DNA double strand breaks (DSBs) in meiosis. Here we used three-color dSTORM microscopy, and a mouse...
10.
Steurer B, Janssens R, Geijer M, Aprile-Garcia F, Geverts B, Theil A, et al.
Nat Commun
. 2022 Jun;
13(1):3624.
PMID: 35750669
The precise regulation of RNA Polymerase II (Pol II) transcription after genotoxic stress is crucial for proper execution of the DNA damage-induced stress response. While stalling of Pol II on...