Agueda Martinez-Barriocanal
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Explore the profile of Agueda Martinez-Barriocanal including associated specialties, affiliations and a list of published articles.
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21
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262
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Recent Articles
1.
Dopeso H, Rodrigues P, Carton-Garcia F, Macaya I, Bilic J, Anguita E, et al.
iScience
. 2024 Mar;
27(4):109400.
PMID: 38523777
Rho GTPases are molecular switches regulating multiple cellular processes. To investigate the role of RhoA in normal intestinal physiology, we used a conditional mouse model overexpressing a dominant negative RhoA...
2.
Matos A, Peres C, Carreira B, Moura L, Acurcio R, Vogel T, et al.
Adv Sci (Weinh)
. 2023 Jul;
10(25):e2300299.
PMID: 37434063
Immune checkpoint blockade reaches remarkable clinical responses. However, even in the most favorable cases, half of these patients do not benefit from these therapies in the long term. It is...
3.
Carton-Garcia F, Brotons B, Anguita E, Dopeso H, Tarragona J, Nieto R, et al.
Oncogene
. 2022 Nov;
41(49):5279-5288.
PMID: 36316444
Colorectal cancer causes >900,000 deaths every year and a deeper understanding of the molecular mechanisms underlying this disease will contribute to improve its clinical management and survival. Myosin Vb (MYO5B)...
4.
Fourniols T, Maggio V, Rafael D, Colaco A, Vidal E, Lopes A, et al.
Eur J Pharm Biopharm
. 2022 Jan;
171:39-49.
PMID: 34998911
Bromodomain and extraterminal domain protein inhibitors (BETi) for cancer treatment did not convince during their first clinical trials. Their epigenetic mechanism of action is still not well understood, even if...
5.
Bazzocco S, Dopeso H, Martinez-Barriocanal A, Anguita E, Nieto R, Li J, et al.
Clin Epigenetics
. 2021 Apr;
13(1):88.
PMID: 33892786
Background: Cancer initiation and progression are driven by genetic and epigenetic changes. Although genome/exome sequencing has significantly contributed to the characterization of the genetic driver alterations, further investigation is required...
6.
Martinez-Barriocanal A, Arango D, Dopeso H
Front Oncol
. 2020 Feb;
10:38.
PMID: 32083000
Whole genome and transcriptome sequencing technologies have led to the identification of many long non-coding RNAs (lncRNAs) and stimulated the research of their role in health and disease. LncRNAs participate...
7.
Montanuy H, Martinez-Barriocanal A, Casado J, Rovirosa L, Ramirez M, Nieto R, et al.
Clin Cancer Res
. 2020 Feb;
26(12):3044-3057.
PMID: 32005748
Purpose: Fanconi anemia rare disease is characterized by bone marrow failure and a high predisposition to solid tumors, especially head and neck squamous cell carcinoma (HNSCC). Patients with Fanconi anemia...
8.
Matos A, Carreira B, Peres C, Moura L, Conniot J, Fourniols T, et al.
J Control Release
. 2019 Jun;
307:108-138.
PMID: 31226355
Colorectal cancer (CRC) is among the five most commonly diagnosed cancers worldwide, constituting 6% of all cancers and the third leading cause of cancer death. CRC is the third and...
9.
Dopeso H, Rodrigues P, Bilic J, Bazzocco S, Carton-Garcia F, Macaya I, et al.
Br J Cancer
. 2017 Dec;
118(1):106-116.
PMID: 29206819
Background: Reduced RHOA signalling has been shown to increase the growth/metastatic potential of colorectal tumours. However, the mechanisms of inactivation of RHOA signalling in colon cancer have not been characterised....
10.
Martinez-Barriocanal A, Arcas-Garcia A, Magallon-Lorenz M, Ejarque-Ortiz A, Negro-Demontel M, Comas-Casellas E, et al.
Sci Rep
. 2017 Oct;
7(1):13544.
PMID: 29051512
Herein, we have used bioinformatics tools to predict five clusters defining ligand-binding sites on the extracellular domain of human CD300b receptor, presumably involved in the formation of both homodimers and...