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Estefania Anguita

Explore the profile of Estefania Anguita including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Tenorio-Castano J, Mansilla Aparicio E, Garcia Santiago F, Klotz C, Regojo R, Anguita E, et al.
Clin Genet . 2024 Aug; 106(6):713-720. PMID: 39191491
Non-immune hydrops fetalis (NIHF) is a rare entity characterized by excessive accumulation of fluid within the fetal extravascular compartments and body cavities. Here we present two intrauterine fetal demises with...
2.
Dopeso H, Rodrigues P, Carton-Garcia F, Macaya I, Bilic J, Anguita E, et al.
iScience . 2024 Mar; 27(4):109400. PMID: 38523777
Rho GTPases are molecular switches regulating multiple cellular processes. To investigate the role of RhoA in normal intestinal physiology, we used a conditional mouse model overexpressing a dominant negative RhoA...
3.
Carton-Garcia F, Brotons B, Anguita E, Dopeso H, Tarragona J, Nieto R, et al.
Oncogene . 2022 Nov; 41(49):5279-5288. PMID: 36316444
Colorectal cancer causes >900,000 deaths every year and a deeper understanding of the molecular mechanisms underlying this disease will contribute to improve its clinical management and survival. Myosin Vb (MYO5B)...
4.
Bazzocco S, Dopeso H, Martinez-Barriocanal A, Anguita E, Nieto R, Li J, et al.
Clin Epigenetics . 2021 Apr; 13(1):88. PMID: 33892786
Background: Cancer initiation and progression are driven by genetic and epigenetic changes. Although genome/exome sequencing has significantly contributed to the characterization of the genetic driver alterations, further investigation is required...
5.
Abdelli F, Jellali K, Anguita E, Gonzalez-Munoz M, Villalobo E, Madronal I, et al.
J Cell Physiol . 2020 Dec; 236(7):4997-5011. PMID: 33305427
The epidermal growth factor receptor (EGFR) harbors a calmodulin (CaM)-binding domain (CaM-BD) and a CaM-like domain (CaM-LD) upstream and downstream, respectively, of the tyrosine kinase (TK) domain. We demonstrate in...
6.
Anguita E, Villalobo A
Arch Biochem Biophys . 2018 May; 650:59-74. PMID: 29753725
Calcium-mediated signaling and the functionality of Src-family tyrosine kinases (SFKs) are two interconnected processes. Activation of these kinases, which are coupled to a series of receptors, mediates Ca mobilization by...
7.
Dopeso H, Rodrigues P, Bilic J, Bazzocco S, Carton-Garcia F, Macaya I, et al.
Br J Cancer . 2017 Dec; 118(1):106-116. PMID: 29206819
Background: Reduced RHOA signalling has been shown to increase the growth/metastatic potential of colorectal tumours. However, the mechanisms of inactivation of RHOA signalling in colon cancer have not been characterised....
8.
Anguita E, Villalobo A
Biochim Biophys Acta Mol Cell Res . 2016 Nov; 1864(6):915-932. PMID: 27818271
In this review, we shall describe the rich crosstalk between non-receptor Src-family kinases (SFKs) and the Ca transient generated in activated cells by a variety of extracellular and intracellular stimuli,...
9.
Stateva S, Salas V, Benguria A, Cossio I, Anguita E, Martin-Nieto J, et al.
Biochem J . 2015 Sep; 472(2):195-204. PMID: 26399481
The activity of calmodulin (CaM) is modulated not only by oscillations in the cytosolic concentration of free Ca(2+), but also by its phosphorylation status. In the present study, the role...
10.
Stateva S, Salas V, Anguita E, Benaim G, Villalobo A
PLoS One . 2015 Jun; 10(6):e0128783. PMID: 26058065
Src family non-receptor tyrosine kinases play a prominent role in multiple cellular processes, including: cell proliferation, differentiation, cell survival, stress response, and cell adhesion and migration, among others. And when...