Aroa Ejarque-Ortiz
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Explore the profile of Aroa Ejarque-Ortiz including associated specialties, affiliations and a list of published articles.
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12
Citations
233
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Recent Articles
1.
Martinez-Barriocanal A, Arcas-Garcia A, Magallon-Lorenz M, Ejarque-Ortiz A, Negro-Demontel M, Comas-Casellas E, et al.
Sci Rep
. 2017 Oct;
7(1):13544.
PMID: 29051512
Herein, we have used bioinformatics tools to predict five clusters defining ligand-binding sites on the extracellular domain of human CD300b receptor, presumably involved in the formation of both homodimers and...
2.
Moshkovits I, Karo-Atar D, Itan M, Reichman H, Rozenberg P, Morgenstern-Ben-Baruch N, et al.
Proc Natl Acad Sci U S A
. 2015 Jul;
112(28):8708-13.
PMID: 26124135
IL-4 receptor (R) α, the common receptor chain for IL-4 and IL-13, is a critical component in IL-4- and IL-13-mediated signaling and subsequent effector functions such as those observed in...
3.
Ejarque-Ortiz A, Sola C, Martinez-Barriocanal A, Schwartz Jr S, Martin M, Peluffo H, et al.
PLoS One
. 2015 May;
10(4):e0123928.
PMID: 25927603
CMRF35-like molecule-1 (CLM-1) belongs to a receptor family mainly expressed in myeloid cells that include activating and inhibitory receptors. CLM-1 contains two ITIMs and a single immunoreceptor tyrosine-based switch motif...
4.
Dentesano G, Straccia M, Ejarque-Ortiz A, Tusell J, Serratosa J, Saura J, et al.
J Neuroinflammation
. 2012 Jul;
9:165.
PMID: 22776069
Background: In physiological conditions, it is postulated that neurons control microglial reactivity through a series of inhibitory mechanisms, involving either cell contact-dependent, soluble-factor-dependent or neurotransmitter-associated pathways. In the current study,...
5.
Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors
Comas-Casellas E, Martinez-Barriocanal A, Miro F, Ejarque-Ortiz A, Schwartz Jr S, Martin M, et al.
J Biol Chem
. 2012 Feb;
287(13):9682-9693.
PMID: 22291008
Herein we present the cloning and molecular characterization of CD300d, a member of the human CD300 family of immune receptors. CD300d cDNA was cloned from RNA obtained from human peripheral...
6.
Straccia M, Gresa-Arribas N, Dentesano G, Ejarque-Ortiz A, Tusell J, Serratosa J, et al.
J Neuroinflammation
. 2011 Nov;
8:156.
PMID: 22074460
Background: Microglia and astrocytes respond to homeostatic disturbances with profound changes of gene expression. This response, known as glial activation or neuroinflammation, can be detrimental to the surrounding tissue. The...
7.
Peluffo H, Ali-Ruiz D, Ejarque-Ortiz A, Heras-Alvarez V, Comas-Casellas E, Martinez-Barriocanal A, et al.
Brain Pathol
. 2011 Sep;
22(3):318-28.
PMID: 21951326
It is well known that cell surface immune receptors play a critical role in regulating immune and inflammatory processes in the central nervous system (CNS). We have analyzed the function...
8.
Ejarque-Ortiz A, Gresa-Arribas N, Straccia M, Mancera P, Sola C, Tusell J, et al.
J Neurosci Res
. 2009 Nov;
88(5):1113-23.
PMID: 19908286
The transcription factor CCAAT/enhancer binding protein delta (C/EBP delta) regulates transcription of genes that play important roles in glial activation. Previous studies have shown the astroglial expression of C/EBP delta...
9.
Tusell J, Ejarque-Ortiz A, Mancera P, Sola C, Saura J, Serratosa J
Glia
. 2008 Sep;
57(5):524-34.
PMID: 18814231
The cdk inhibitor p21(Cip1), also named p21(Cip1/Waf1), is intimately involved in coupling growth arrest to cellular differentiation in several cell types. p21(Cip1) is a multifunctional protein that might regulate cell-cycle...
10.
Gorina R, Santalucia T, Petegnief V, Ejarque-Ortiz A, Saura J, Planas A
Glia
. 2008 Aug;
57(1):93-107.
PMID: 18709661
Short interfering RNA (siRNA) inhibits the synthesis of specific proteins through RNA interference (RNAi). However, siRNA can induce innate immune responses that are mediated by toll-like receptors (TLRs) in cells...