Adrian E Morelli
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Explore the profile of Adrian E Morelli including associated specialties, affiliations and a list of published articles.
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79
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5580
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Recent Articles
1.
Powell J, Gandley R, Lackner E, Dolinish A, Ouyang Y, Powers R, et al.
Pregnancy Hypertens
. 2022 Mar;
28:66-73.
PMID: 35240546
Preeclampsia (PE) is a common syndrome of pregnancy, characterized by new-onset hypertension and proteinuria after gestational week 20, or new onset of hypertension and significant end-organ dysfunction. In the worst...
2.
Morelli A, Sadovsky Y
Immunol Rev
. 2022 Feb;
308(1):105-122.
PMID: 35199366
The mechanisms underlying maternal tolerance of the semi- or fully-allogeneic fetus are intensely investigated. Across gestation, feto-placental antigens interact with the maternal immune system locally within the trophoblast-decidual interface and...
3.
Bandyopadhyay M, Morelli A, Balmert S, Ward N, Erdos G, Sumpter T, et al.
J Allergy Clin Immunol
. 2022 Jan;
150(1):114-130.
PMID: 35085664
Background: Allergic contact dermatitis (CD) is a chronic inflammatory skin disease caused by type 1 biased adaptive immunity for which there is an unmet need for antigen (Ag)-specific immunotherapies. Exposure...
4.
Zeng F, Chen Z, Chen R, Shufesky W, Bandyopadhyay M, Camirand G, et al.
Sci Transl Med
. 2021 Mar;
13(585).
PMID: 33731430
Despite the role of donor-specific antibodies (DSAs) in recognizing major histocompatibility complex (MHC) antigens and mediating transplant rejection, how and where recipient B cells in lymphoid tissues encounter donor MHC...
5.
Sadovsky Y, Ouyang Y, Powell J, Li H, Mouillet J, Morelli A, et al.
Placenta
. 2020 Nov;
102:34-38.
PMID: 33218576
The discovery of regulated trafficking of extracellular vesicles (EVs) has added a new dimension to our understanding of local and distant communication among cells and tissues. Notwithstanding the expanded landscape...
6.
Morelli A, Sumpter T, Rojas-Canales D, Bandyopadhyay M, Chen Z, Tkacheva O, et al.
Cell Rep
. 2020 Mar;
30(10):3448-3465.e8.
PMID: 32160549
Efficient Ca flux induced during cognate T cell activation requires signaling the T cell receptor (TCR) and unidentified G-protein-coupled receptors (GPCRs). T cells express the neurokinin-1 receptor (NK1R), a GPCR...
7.
Hughes A, Zhao D, Dai H, Abou-Daya K, Tieu R, Rammal R, et al.
J Clin Invest
. 2019 Nov;
130(1):287-294.
PMID: 31763998
Activation of host T cells that mediate allograft rejection is a 2-step process. The first occurs in secondary lymphoid organs where T cells encounter alloantigens presented by host DCs and...
8.
Chen Z, Larregina A, Morelli A
Curr Opin Organ Transplant
. 2019 Oct;
24(6):670-678.
PMID: 31592838
Purpose Of Review: Extracellular vesicles released by prokaryote or eukaryote cells are emerging as mechanisms of cell-to-cell communication, by either physically interacting with the surface of target cells or transferring...
9.
Vats R, Brzoska T, Bennewitz M, Jimenez M, Pradhan-Sundd T, Tutuncuoglu E, et al.
Am J Respir Crit Care Med
. 2019 Sep;
201(1):33-46.
PMID: 31498653
Intraerythrocytic polymerization of Hb S promotes hemolysis and vasoocclusive events in the microvasculature of patients with sickle cell disease (SCD). Although platelet-neutrophil aggregate-dependent vasoocclusion is known to occur in the...
10.
Friedrich A, Campo V, Cela E, Morelli A, Shufesky W, Tckacheva O, et al.
Eur J Immunol
. 2019 Jul;
49(11):2095-2102.
PMID: 31334839
There is increasing evidence of the relevant connection and regulation between the gut and skin immune axis. In fact, oral administration of lipoteichoic acid (LTA) from Lactobacillus rhamnosus GG (LGG)...