A J Coyle
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Explore the profile of A J Coyle including associated specialties, affiliations and a list of published articles.
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69
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2489
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Recent Articles
1.
Huard C, Gulla S, Bennett D, Coyle A, Vleugels R, Greenberg S
Br J Dermatol
. 2016 Aug;
176(5):1224-1230.
PMID: 27564228
Background: Dermatomyositis (DM) is an autoimmune disease primarily affecting skin and muscle. Objectives: The purpose of this study was to determine whether an association exists between clinical skin disease activity...
2.
3.
Al-Garawi A, Fattouh R, Botelho F, Walker T, Goncharova S, Moore C, et al.
Mucosal Immunol
. 2011 Sep;
4(6):682-94.
PMID: 21881572
The origins of allergic asthma, particularly in infancy, remain obscure. Respiratory viral infections and allergen sensitization in early life have been associated with asthma in young children. However, a causal...
4.
Botelho F, Nikota J, Bauer C, Davis N, Cohen E, Anderson I, et al.
Eur Respir J
. 2011 Mar;
38(2):285-94.
PMID: 21436349
We investigated the role of granulocyte-macrophage colony-stimulating factor (GM-CSF) in a subchronic exposure model of cigarette smoke (CS)-induced inflammation using antibodies directed against GM-CSF or the GM-CSF receptor (GM-CSFR) α-chain....
5.
Perros F, Hoogsteden H, Coyle A, Lambrecht B, Hammad H
Allergy
. 2009 Jul;
64(7):995-1002.
PMID: 19630858
Background: As Th2 type lymphocytes orchestrate the cardinal features of allergic asthma, inhibiting their recruitment to the lungs could be of therapeutic benefit. Although human Th2 cells express the CCR4...
6.
Sun J, Wong B, Cundall M, Goncharova S, Conway M, Dalrymple A, et al.
Clin Exp Allergy
. 2007 May;
37(6):901-8.
PMID: 17517104
Background: Seasonal rhinitis is manifested by a series of nasal symptoms in response to exposure to seasonal allergens including ragweed pollen. Understanding its immunological mechanisms may help to better manage...
7.
Ritz S, Cundall M, Gajewska B, Swirski F, Wiley R, Alvarez D, et al.
Clin Exp Immunol
. 2004 Oct;
138(2):213-20.
PMID: 15498029
Originally defined by their patterns of cytokine production, Th1 and Th2 cells have been described more recently to express other genes differentially as well, at least in vitro. In this...
8.
Swirski F, Gajewska B, Alvarez D, Ritz S, Cundall M, Cates E, et al.
Clin Exp Allergy
. 2002 Apr;
32(3):411-21.
PMID: 11940072
Background: Exposure to aerosolized harmless antigen such as ovalbumin (OVA) has previously been shown to induce inhalation tolerance, a state characterized by inhibition of IgE synthesis and airway inflammation, upon...
9.
Morra M, Lu J, POY F, Martin M, Sayos J, Calpe S, et al.
EMBO J
. 2001 Nov;
20(21):5840-52.
PMID: 11689425
The T and natural killer (NK) cell-specific gene SAP (SH2D1A) encodes a 'free SH2 domain' that binds a specific tyrosine motif in the cytoplasmic tail of SLAM (CD150) and related...
10.
Gajewska B, Swirski F, Alvarez D, Ritz S, Goncharova S, Cundall M, et al.
Am J Respir Cell Mol Biol
. 2001 Oct;
25(3):326-34.
PMID: 11588010
The objective of this study was to define phenotypic changes of antigen-presenting cells (APCs) and T cells in a murine model of antigen-induced airways inflammation that involves intraperitoneal sensitization with...