C G Irvin
Overview
Explore the profile of C G Irvin including associated specialties, affiliations and a list of published articles.
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Articles
105
Citations
2398
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Recent Articles
1.
Chapman D, Mougey E, Van der Velden J, Lahue K, Aliyeva M, Daphtary N, et al.
Clin Exp Allergy
. 2017 May;
47(9):1214-1222.
PMID: 28471517
Background: The Duffy antigen receptor for chemokines (DARC) is an atypical receptor that regulates pro-inflammatory cytokines. However, the role of DARC in asthma pathophysiology is unknown. Objective: To determine the...
2.
Dahlin A, Litonjua A, Irvin C, Peters S, Lima J, Kubo M, et al.
Pharmacogenomics J
. 2015 Jun;
16(2):151-7.
PMID: 26031901
Heterogeneous therapeutic responses to leukotriene modifiers (LTMs) are likely due to variation in patient genetics. Although prior candidate gene studies implicated multiple pharmacogenetic loci, to date, no genome-wide association study...
3.
Chapman D, Irvin C
Clin Exp Allergy
. 2015 Feb;
45(4):706-19.
PMID: 25651937
Airway hyper-responsiveness (AHR) has long been considered a cardinal feature of asthma. The development of the measurement of AHR 40 years ago initiated many important contributions to our understanding of...
4.
Duan Q, Lasky-Su J, Himes B, Qiu W, Litonjua A, Damask A, et al.
Pharmacogenomics J
. 2013 Mar;
14(1):41-7.
PMID: 23508266
Reversibility of airway obstruction in response to β2-agonists is highly variable among asthmatics, which is partially attributed to genetic factors. In a genome-wide association study of acute bronchodilator response (BDR)...
5.
Lasky-Su J, Himes B, Raby B, Klanderman B, Sylvia J, Lange C, et al.
Clin Exp Allergy
. 2012 Nov;
42(12):1724-33.
PMID: 23181788
Background: Asthma is a common chronic respiratory disease in children and adults. An important genetic component to asthma susceptibility has long been recognized, most recently through the identification of several...
6.
Duan Q, Du R, Lasky-Su J, Klanderman B, Partch A, Peters S, et al.
Pharmacogenomics J
. 2012 Jan;
13(2):130-6.
PMID: 22212731
A pro-asthmatic culture milieu and β2-agonist (isoproterenol) were previously shown to regulate the expression of select transcription factors (TFs) within human airway epithelial and smooth muscle cells. This study tests...
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9.
Lundblad L, Irvin C, Hantos Z, Sly P, Mitzner W, Bates J
Eur Respir J
. 2007 Oct;
30(4):805.
PMID: 17906089
No abstract available.
10.
An S, Bai T, Bates J, Black J, Brown R, Brusasco V, et al.
Eur Respir J
. 2007 May;
29(5):834-60.
PMID: 17470619
Excessive airway obstruction is the cause of symptoms and abnormal lung function in asthma. As airway smooth muscle (ASM) is the effecter controlling airway calibre, it is suspected that dysfunction...