Implementing FAIR Data Management Within the German Network for Bioinformatics Infrastructure (de.NBI) Exemplified by Selected Use Cases
Overview
Authors
Affiliations
This article describes some use case studies and self-assessments of FAIR status of de.NBI services to illustrate the challenges and requirements for the definition of the needs of adhering to the FAIR (findable, accessible, interoperable and reusable) data principles in a large distributed bioinformatics infrastructure. We address the challenge of heterogeneity of wet lab technologies, data, metadata, software, computational workflows and the levels of implementation and monitoring of FAIR principles within the different bioinformatics sub-disciplines joint in de.NBI. On the one hand, this broad service landscape and the excellent network of experts are a strong basis for the development of useful research data management plans. On the other hand, the large number of tools and techniques maintained by distributed teams renders FAIR compliance challenging.
Temporal phosphoproteomics reveals circuitry of phased propagation in insulin signaling.
Turewicz M, Skagen C, Hartwig S, Majda S, Thedinga K, Herwig R Nat Commun. 2025; 16(1):1570.
PMID: 39939313 PMC: 11821911. DOI: 10.1038/s41467-025-56335-6.
de Groot R, van der Graaff F, van der Doelen D, Luijten M, De Meyer R, Alrouh H JMIR Ment Health. 2024; 11:e59113.
PMID: 39727091 PMC: 11683739. DOI: 10.2196/59113.
Creating cloud platforms for supporting FAIR data management in biomedical research projects.
Jentsch M, Schneider-Lunitz V, Taron U, Braun M, Ishaque N, Wagener H F1000Res. 2024; 13:8.
PMID: 38779317 PMC: 11109697. DOI: 10.12688/f1000research.140624.3.
Ontologies for increasing the FAIRness of plant research data.
Dumschott K, Dorpholz H, Laporte M, Brilhaus D, Schrader A, Usadel B Front Plant Sci. 2023; 14:1279694.
PMID: 38098789 PMC: 10720748. DOI: 10.3389/fpls.2023.1279694.
Ten simple rules for starting FAIR discussions in your community.
Belliard F, Maineri A, Plomp E, Ramos Padilla A, Sun J, Zare Jeddi M PLoS Comput Biol. 2023; 19(12):e1011668.
PMID: 38096152 PMC: 10721007. DOI: 10.1371/journal.pcbi.1011668.