Steve Hoffmann
Overview
Explore the profile of Steve Hoffmann including associated specialties, affiliations and a list of published articles.
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97
Citations
3985
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Recent Articles
1.
Vromman M, Anckaert J, Bortoluzzi S, Buratin A, Chen C, Chu Q, et al.
Nat Methods
. 2025 Jan;
22(2):448.
PMID: 39825083
No abstract available.
2.
Wiechens E, Vigliotti F, Siniuk K, Schwarz R, Schwab K, Riege K, et al.
Nat Genet
. 2025 Jan;
57(1):206-217.
PMID: 39779959
Convergent transcription, that is, the collision of sense and antisense transcription, is ubiquitous in mammalian genomes and believed to diminish RNA expression. Recently, antisense transcription downstream of promoters was found...
3.
Waikar S, Mogg R, Baker A, Frendl G, Topper M, Adler S, et al.
Clin Pharmacol Ther
. 2025 Jan;
PMID: 39754474
Two observational studies were conducted to support an initiative to qualify translational kidney safety biomarkers as clinical drug development tools that identify tubular injury prior to changes in estimated glomerular...
4.
Sahm A, Riege K, Groth M, Bens M, Kraus J, Fischer M, et al.
Genome Res
. 2024 Dec;
34(12):2217-2228.
PMID: 39632086
Growing evidence suggests that somatic mutations may be a major cause of the aging process. However, it remains to be tested whether the predictions of the theory also apply to...
5.
Stein G, Aly J, Lange L, Manzolillo A, Riege K, Brancato A, et al.
Mol Psychiatry
. 2024 Oct;
PMID: 39433904
Chronic stress is a major risk factor for depression, a leading cause of disability and suicide. Because current antidepressants work slowly, have common side effects, and are only effective in...
6.
Schwab K, Riege K, Coronel L, Stanko C, Forste S, Hoffmann S, et al.
Cell Death Discov
. 2024 Aug;
10(1):376.
PMID: 39181888
The transcription factor regulatory factor X 7 (RFX7) has been identified as a tumor suppressor that is recurrently mutated in lymphoid cancers and appears to be dysregulated in many other...
7.
Travaglia A, Hoffmann S
Alzheimers Dement
. 2024 Jul;
20(10):7395-7398.
PMID: 39077997
The COVID pandemic has shown that when the research community comes together, we can conquer the most complex biomedical challenges. Collaboration and teamwork among federal agencies, private organizations, and researchers...
8.
Stein G, Aly J, Manzolillo A, Lange L, Riege K, Hussain I, et al.
Biol Psychiatry
. 2024 Jul;
97(1):54-63.
PMID: 39029777
Background: Chronic stress significantly contributes to mood and anxiety disorders. Previous data suggest a correlative connection between vitamin B12 supplementation, depression, and stress resilience. However, the underlying mechanisms are still...
9.
Olecka M, van Bommel A, Best L, Haase M, Foerste S, Riege K, et al.
Nat Commun
. 2024 Apr;
15(1):3074.
PMID: 38594255
Although DNA methylation data yields highly accurate age predictors, little is known about the dynamics of this quintessential epigenomic biomarker during lifespan. To narrow the gap, we investigate the methylation...
10.
Kirchner T, Riege K, Hoffmann S
Sci Rep
. 2024 Feb;
14(1):4872.
PMID: 38418837
Arguably, the most important tool for many computational scientists is the Linux shell. Processing steps carried out there are critical for a large number of analyses. While the manual documentation...