Respiratory Microbial Co-infection With SARS-CoV-2

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2020 Sep 28

PMID 32983056

Citations 37

Authors

Bill W Massey

Karuna Jayathilake

Herbert Y Meltzer

Affiliations

Soon will be listed here.

Abstract

Co-infection with additional pathogens is a well-known feature of pandemics. We determined the prevalence and type of a wide variety of respiratory pathogens in 12,075 United States subjects tested for SARS-CoV-2 infection in March and April 2020. Infections with other respiratory pathogens, which on their own produce at least some SARS-CoV-2 symptoms including mortality, were present in both SARS-CoV-2 + and SARS-CoV-2- subjects. Non-SARS-CoV-2 infection rates were significantly higher in SARS-CoV-2 + (86%) patients than SARS-CoV-2- patients (76%) ( < 0.0001). Among the co-pathogens present in both subject groups were and which can produce serious respiratory illness on their own, Advanced age and nursing home status were associated with higher SARS-CoV-2 + and co-infection rates. Testing for the presence of co-pathogens going forward will assist in the diagnosis and optimal treatment of suspected SARS-CoV-2 respiratory infections in the current pandemic.

Citing Articles

Prevalence of bacteria, fungi, and virus coinfections with SARS-CoV-2 Omicron variant among patients with severe COVID-19 in Guangzhou, China, winter 2022.

Fan Q, Jiang M, Zhang J, Tang G, Gao M, Wen Y Biosaf Health. 2025; 6(2):92-97.

PMID: 40078947 PMC: 11895009. DOI: 10.1016/j.bsheal.2024.02.003.

Bacterial co-infection in COVID-19: a call to stay vigilant.

Liu S, Yu C, Tu Q, Zhang Q, Fu Z, Huang Y PeerJ. 2024; 12:e18041.

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Co-Infection of SARS-CoV-2 and : A Systematic Review and Meta-Analysis.

Chagas A, Araujo J, Serra J, Araujo K, Cunha M, Correia A Diagnostics (Basel). 2024; 14(11).

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Towards Understanding and Identification of Human Viral Co-Infections.

Wu H, Zhou H, Zheng H, Wu A Viruses. 2024; 16(5).

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Lu Y, Wang C, Wang Y, Chen Y, Zhao L, Li Y Front Cell Infect Microbiol. 2024; 13:1320933.

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