Herbert Y Meltzer
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Explore the profile of Herbert Y Meltzer including associated specialties, affiliations and a list of published articles.
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299
Citations
8035
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Recent Articles
1.
Schneider-Thoma J, Hamza T, Chalkou K, Siafis S, Dong S, Bighelli I, et al.
Lancet Psychiatry
. 2025 Mar;
PMID: 40023172
Background: Clozapine is recommended by national and international guidelines for people with treatment-resistant schizophrenia. However, available meta-analyses of randomised controlled trials have not shown superior efficacy of clozapine when compared...
2.
Yoshikawa A, Li J, Alliey-Rodriguez N, Meltzer H
Pharmacogenomics J
. 2025 Feb;
25(2):3.
PMID: 39979276
Prediction of treatment response by genetic biomarkers has potential for clinical use and contributes to the understanding of pathophysiology and drug mechanism of action. The purpose of this study is...
3.
Arshadi M, Elmaadawi A, Nasr S, Jayathilake K, Rassnick S, Ford L, et al.
J Clin Psychopharmacol
. 2024 Sep;
44(5):481-491.
PMID: 39250138
Background: The serotonin type 7 (5-HT7) receptor is one of 14 5-HT receptors. It has received attention for its possible role in mood disorders and cognition. The 5-HT7 receptor antagonist,...
4.
Wang R, Lu J, Herbert D, Lieberman J, Meltzer H, Tiwari A, et al.
Hum Psychopharmacol
. 2024 Apr;
39(4):e2898.
PMID: 38676936
Objectives: The pathology of Tardive Dyskinesia (TD) has yet to be fully understood, but there have been proposed hypotheses for the cause of this condition. Our team previously reported a...
5.
Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, et al.
Elife
. 2024 Mar;
12.
PMID: 38529532
Increased levels of lactate, an end-product of glycolysis, have been proposed as a potential surrogate marker for metabolic changes during neuronal excitation. These changes in lactate levels can result in...
6.
Lee M, Cola P, Jayathilake K, Meltzer H
J Clin Psychopharmacol
. 2023 Nov;
43(6):555-556.
PMID: 37930220
No abstract available.
7.
Rajagopal L, Mahjour S, Huang M, Ryan C, Elzokaky A, Csakai A, et al.
Behav Brain Res
. 2023 Aug;
454:114614.
PMID: 37572758
The serotonin (5-HT) receptor(R) is a widely distributed G-protein-coupled receptor, expressed abundantly in the central nervous system. Alstonine is a natural product that has significant properties of atypical antipsychotic drugs...
8.
Yoshida K, Marshe V, Elsheikh S, Maciukiewicz M, Tiwari A, Brandl E, et al.
Pharmacogenomics J
. 2023 Apr;
23(5):119-126.
PMID: 37106021
Given the polygenic nature of antipsychotic-induced weight gain (AIWG), we investigated whether polygenic risk scores (PRS) for various psychiatric and metabolic traits were associated with AIWG. We included individuals with...
9.
Lee M, Cola P, Jayathilake K, Meltzer H
J Clin Psychopharmacol
. 2023 Mar;
43(3):211-219.
PMID: 36975722
Purpose/background: The favorable effect of clozapine on psychotic symptoms in patients with treatment-resistant (TR) schizophrenia (SCZ) in short-term studies is well established. However, prospective studies of the long-term outcome of...
10.
Suzuki K, Yamasaki S, Miyashita M, Ando S, Toriumi K, Yoshikawa A, et al.
Schizophrenia (Heidelb)
. 2022 Jul;
8(1):44.
PMID: 35853893
Muscular strength, assessed by handgrip, is a risk indicator for psychiatric disorders, including psychosis. However, the biological mechanisms underlying this association remain unclear. Since advanced glycation end products (AGEs) play...