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Going with the Flow: from Circulating Tumor Cells to DNA

Overview
Journal Sci Transl Med
Date 2013 Oct 18
PMID 24132635
Citations 58
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Abstract

Molecular analyses of circulating tumor DNA (ctDNA) in plasma from cancer patients have the potential to deliver minimally invasive diagnostic and disease-monitoring biomarkers. Drawing from experience gained through the translation of circulating tumor cell detection to clinical tests, we discuss ctDNA as a source of tumor material for biomarker development.

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