Zohar Shipony
Overview
Explore the profile of Zohar Shipony including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
2154
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0
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Recent Articles
11.
King H, Wells K, Shipony Z, Kathiria A, Wagar L, Lareau C, et al.
Sci Immunol
. 2021 Oct;
6(64):eabh3768.
PMID: 34623901
The germinal center (GC) response is critical for both effective adaptive immunity and establishing peripheral tolerance by limiting autoreactive B cells. Dysfunction in these processes can lead to defective immune...
12.
Marinov G, Shipony Z
Methods Mol Biol
. 2021 Feb;
2243:183-226.
PMID: 33606259
The ATAC-seq assay has emerged as the most useful, versatile, and widely adaptable method for profiling accessible chromatin regions and tracking the activity of cis-regulatory elements (cREs) in eukaryotes. Thanks...
13.
Maor-Nof M, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang Y, Couthouis J, et al.
Cell
. 2021 Jan;
184(3):689-708.e20.
PMID: 33482083
The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is a GGGGCC repeat expansion in the C9orf72 gene. We developed a platform to interrogate the...
14.
Wenderski W, Wang L, Krokhotin A, Walsh J, Li H, Shoji H, et al.
Proc Natl Acad Sci U S A
. 2020 Apr;
117(18):10055-10066.
PMID: 32312822
Synaptic activity in neurons leads to the rapid activation of genes involved in mammalian behavior. ATP-dependent chromatin remodelers such as the BAF complex contribute to these responses and are generally...
15.
Shipony Z, Marinov G, Swaffer M, Sinnott-Armstrong N, Skotheim J, Kundaje A, et al.
Nat Methods
. 2020 Feb;
17(3):319-327.
PMID: 32042188
Mapping open chromatin regions has emerged as a widely used tool for identifying active regulatory elements in eukaryotes. However, existing approaches, limited by reliance on DNA fragmentation and short-read sequencing,...
16.
Manaster Y, Shipony Z, Hutzler A, Kolesnikov M, Avivi C, Shalmon B, et al.
Cancer Immunol Immunother
. 2019 Jun;
68(8):1287-1301.
PMID: 31253998
Patchy infiltration of tumors by cytotoxic T cells (CTLs) predicts poorer prognosis for cancer patients. The factors limiting intratumoral CTL dissemination, though, are poorly understood. To study CTL dissemination in...
17.
Klemm S, Shipony Z, Greenleaf W
Nat Rev Genet
. 2019 Jan;
20(4):207-220.
PMID: 30675018
Physical access to DNA is a highly dynamic property of chromatin that plays an essential role in establishing and maintaining cellular identity. The organization of accessible chromatin across the genome...
18.
Tovy A, Spiro A, McCarthy R, Shipony Z, Aylon Y, Allton K, et al.
Genes Dev
. 2018 Oct;
32(19-20):1358.
PMID: 30275045
No abstract available.
19.
Tovy A, Spiro A, McCarthy R, Shipony Z, Aylon Y, Allton K, et al.
Genes Dev
. 2017 Jun;
31(10):959-972.
PMID: 28607180
DNA methylation is a key regulator of embryonic stem cell (ESC) biology, dynamically changing between naïve, primed, and differentiated states. The p53 tumor suppressor is a pivotal guardian of genomic...
20.
Gafni O, Weinberger L, AlFatah Mansour A, Manor Y, Chomsky E, Ben-Yosef D, et al.
Nature
. 2015 Apr;
520(7549):710.
PMID: 25830888
No abstract available.