Zizhen Kang
Overview
Explore the profile of Zizhen Kang including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
35
Citations
1318
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wang Y, Ghimire S, Mangalam A, Kang Z
bioRxiv
. 2025 Jan;
PMID: 39764033
Oligodendroglial lineage cells (OLCs) are critical for neuronal support functions, including myelination and remyelination. Emerging evidence reveals their active roles in neuroinflammation, particularly in conditions like Multiple Sclerosis (MS). This...
2.
Wang Y, Gao J, Sakaguchi T, Maretzky T, Gurung P, Narayanan N, et al.
Cells
. 2024 Apr;
13(7.
PMID: 38607004
Leucine-rich repeat kinase 2 (LRRK2) is a serine-threonine protein kinase belonging to the ROCO protein family. Within the kinase domain of LRRK2, a point mutation known as LRRK2 G2019S has...
3.
Wang Y, Gao J, Sakaguchi T, Maretzky T, Gurung P, Short S, et al.
bioRxiv
. 2023 Jul;
PMID: 37425755
LRRK2 G2019S is the most prevalent variant associated with Parkinson's disease (PD), found in 1-3% of sporadic and 4-8% of familial PD cases. Intriguingly, emerging clinical studies have suggested that...
4.
Liu W, Zhou H, Wang H, Zhang Q, Zhang R, Willard B, et al.
Nat Commun
. 2022 May;
13(1):2748.
PMID: 35585086
Toll-like receptors/Interleukin-1 receptor signaling plays an important role in high-fat diet-induced adipose tissue dysfunction contributing to obesity-associated metabolic syndromes. Here, we show an unconventional IL-1R-IRAKM-Slc25a1 signaling axis in adipocytes that...
5.
Zhang Q, Liu W, Wang H, Zhou H, Bulek K, Chen X, et al.
Nat Commun
. 2022 May;
13(1):2406.
PMID: 35504893
The C-type lectin receptor Mincle is known for its important role in innate immune cells in recognizing pathogen and damage associated molecular patterns. Here we report a T cell-intrinsic role...
6.
Zhao J, Liao Y, Miller-Little W, Xiao J, Liu C, Li X, et al.
J Neuroinflammation
. 2021 Apr;
18(1):98.
PMID: 33879167
Background: Multiple sclerosis (MS) is a debilitating neurological disease caused by autoimmune destruction of the myelin sheath. Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for the pathogenesis...
7.
Bulek K, Zhao J, Liao Y, Rana N, Corridoni D, Antanaviciute A, et al.
J Clin Invest
. 2020 Jun;
130(8):4218-4234.
PMID: 32597834
Gasdermin D (GSDMD) induces pyroptosis via the pore-forming activity of its N-terminal domain, cleaved by activated caspases associated with the release of IL-1β. Here, we report a nonpyroptotic role of...
8.
Zhang M, Yao C, Cai J, Liu S, Liu X, Chen Y, et al.
J Transl Med
. 2019 Jan;
17(1):37.
PMID: 30670047
Background: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by the presence of pathogenic autoantibodies associated with polyclonal B cell hyperreactivity. Previous study reported that autophagy-related gene Leucine-rich...
9.
Zhang C, Jiang M, Zhou H, Liu W, Wang C, Kang Z, et al.
J Clin Invest
. 2018 Oct;
128(12):5399-5412.
PMID: 30372424
NLRP3 inflammasome plays a critical spatiotemporal role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). This study reports a mechanistic insight into noncanonical NLRP3 inflammasome activation in microglia for the...
10.
Song F, Hong X, Cao J, Ma G, Han Y, Cepeda C, et al.
Commun Biol
. 2018 Oct;
1:80.
PMID: 30271961
The contribution of the inwardly rectifying K channel subtype Kir4.1 has been focused mainly on astrocytes, where they play important roles in the maintenance of resting membrane potential, extracellular K...