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Caini Liu

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Articles 44
Citations 2113
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Recent Articles
1.
Ta H, Roy D, Zhang K, Alban T, Juric I, Dong J, et al.
Sci Immunol . 2024 May; 9(95):eadi7418. PMID: 38758807
Immune checkpoint blockade is a promising approach to activate antitumor immunity and improve the survival of patients with cancer. V-domain immunoglobulin suppressor of T cell activation (VISTA) is an immune...
2.
Miller-Little W, Chen X, Salazar V, Liu C, Bulek K, Zhou J, et al.
Sci Immunol . 2024 May; 9(95):eabq1558. PMID: 38701190
Steroid resistance poses a major challenge for the management of autoimmune neuroinflammation. T helper 17 (T17) cells are widely implicated in the pathology of steroid resistance; however, the underlying mechanisms...
3.
Xiao J, Chen X, Liu W, Qian W, Bulek K, Hong L, et al.
JCI Insight . 2023 Aug; 8(18). PMID: 37607012
Tumor necrosis factor receptor-associated factor 4 (TRAF4) is an important regulator of type 2 responses in the airway; however, the underlying cellular and molecular mechanisms remain elusive. Herein, we generated...
4.
Xiao J, Chen X, Liu W, Qian W, Bulek K, Hong L, et al.
bioRxiv . 2023 Feb; PMID: 36798382
Tumor necrosis factor receptor (TNF)-associated factor 4 (TRAF4) is an important regulator of type 2 responses in the airway; however, the underlying cellular and molecular mechanisms remain elusive. Herein, we...
5.
Hong L, Herjan T, Bulek K, Xiao J, Comhair S, Erzurum S, et al.
J Immunol . 2022 Nov; 209(10):1860-1869. PMID: 36426949
IL-17A plays an important role in the pathogenesis of asthma, particularly the neutrophilic corticosteroid (CS)-resistant subtype of asthma. Clinical studies suggest that a subset of asthma patients, i.e., Th17/IL-17A-mediated (type...
6.
Liu W, Zhou H, Wang H, Zhang Q, Zhang R, Willard B, et al.
Nat Commun . 2022 May; 13(1):2748. PMID: 35585086
Toll-like receptors/Interleukin-1 receptor signaling plays an important role in high-fat diet-induced adipose tissue dysfunction contributing to obesity-associated metabolic syndromes. Here, we show an unconventional IL-1R-IRAKM-Slc25a1 signaling axis in adipocytes that...
7.
Zhang Q, Liu W, Wang H, Zhou H, Bulek K, Chen X, et al.
Nat Commun . 2022 May; 13(1):2406. PMID: 35504893
The C-type lectin receptor Mincle is known for its important role in innate immune cells in recognizing pathogen and damage associated molecular patterns. Here we report a T cell-intrinsic role...
8.
Chen X, Zhao J, Herjan T, Hong L, Liao Y, Liu C, et al.
J Exp Med . 2022 Apr; 219(6). PMID: 35389431
Increasing evidence suggests that intratumoral inflammation has an outsized influence on antitumor immunity. Here, we report that IL-17, a proinflammatory cytokine widely associated with poor prognosis in solid tumors, drives...
9.
Fu D, Pfannenstiel L, Demelash A, Phoon Y, Mayell C, Cabrera C, et al.
Cell Death Dis . 2022 Jan; 13(1):63. PMID: 35042842
Colorectal cancer (CRC) is one of the most common and deadliest forms of cancer. Myeloid Cell Leukemia 1 (MCL1), a pro-survival member of the Bcl-2 protein family is associated with...
10.
Liu C, Zhang M, Gao H, Kong L, Fan S, Wang L, et al.
Water Res . 2021 Dec; 209:117904. PMID: 34864621
The incomplete removal of N-nitrosamines in water through current degraded techniques and the carcinogenicity of N-nitrosamines call for alternative complete and safe removal approaches. Here, we describe a cyclic coupling...