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Zhongju Lu

Explore the profile of Zhongju Lu including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 837
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Recent Articles
1.
Ghafary I, Kim C, Roth E, Lu M, Taub E, Lee S, et al.
Cardiooncology . 2023 May; 9(1):25. PMID: 37208762
Objective: To investigate the association between stages of QTc prolongation and the risk of cardiac events among patients on TKIs. Methods: This was a retrospective cohort study performed at an...
2.
Lu Z, Luu Y, Ip J, Husain I, Lu M, Kim C, et al.
J Community Hosp Intern Med Perspect . 2021 Nov; 11(6):799-807. PMID: 34804394
To assess the prevalence of QTc prolongation in both non-diabetic and diabetic patients on TKIs. Some TKIs have been reported to cause QTc prolongation, which is prevalent in diabetes. However,...
3.
Lin Y, Grinter S, Lu Z, Xu X, Wang H, Liang H, et al.
Proc Natl Acad Sci U S A . 2021 May; 118(20). PMID: 33990467
Cardiac arrhythmias are the most common cause of sudden cardiac death worldwide. Lengthening the ventricular action potential duration (APD), either congenitally or via pathologic or pharmacologic means, predisposes to a...
4.
Lu Z, Wang H, Gordon C, Ballou L, Lin R, Cohen I
Front Physiol . 2020 Nov; 11:587040. PMID: 33240105
It has long been known that heart rate is regulated by the autonomic nervous system. Recently, we demonstrated that the pacemaker current, I , is regulated by phosphoinositide 3-kinase (PI3K)...
5.
Lin R, Lu Z, Anyukhovsky E, Jiang Y, Wang H, Gao J, et al.
J Gen Physiol . 2019 Jun; 151(8):1051-1058. PMID: 31217223
Heart rate in physiological conditions is set by the sinoatrial node (SN), the primary cardiac pacing tissue. Phosphoinositide 3-kinase (PI3K) signaling is a major regulatory pathway in all normal cells,...
6.
Lu Z, Lense L, Sharma M, Shah A, Luu Y, Cardinal L, et al.
J Community Hosp Intern Med Perspect . 2017 Jun; 7(2):87-94. PMID: 28638571
: To evaluate the prevalence and longitudinal changes of prolonged QTc in DM patients admitted to our community hospital, and to determine, if any, its correlation with changes of left...
7.
Guo Y, Lu Z, Cohen I, Scarlata S
Stem Cells Transl Med . 2015 Mar; 4(5):476-82. PMID: 25769653
Stem cell therapy requires a nontoxic and high-throughput method to achieve a pure cell population to prevent teratomas that can occur if even one cell in the implant has not...
8.
Sai W, Yu M, Wei M, Lu Z, Zheng Y, Wang Y, et al.
Clin Exp Pharmacol Physiol . 2014 Feb; 41(4):301-8. PMID: 24552423
It has been reported that bitter tastants decrease blood pressure and relax precontracted vascular smooth muscle. However, the underlying mechanisms remain unclear. The aim of the present study was to...
9.
Li Y, Gao J, Lu Z, McFarland K, Shi J, Bock K, et al.
Proc Natl Acad Sci U S A . 2013 Nov; 110(47):18922-7. PMID: 24190995
Gating of ion channels by ligands is fundamental to cellular function, and ATP serves as both an energy source and a signaling molecule that modulates ion channel and transporter functions....
10.
Williams J, Xu J, Lu Z, Klimas A, Chen X, Ambrosi C, et al.
PLoS Comput Biol . 2013 Sep; 9(9):e1003220. PMID: 24068903
Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as new excitatory optogenetic tools not only in neuroscience, but also in other areas, including cardiac electrophysiology. An accurate...