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Peter Danilo Jr

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Articles 40
Citations 989
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Recent Articles
1.
Dun W, Danilo Jr P, Mohler P, Boyden P
Life Sci . 2018 Mar; 201:72-80. PMID: 29534991
Aim: Our objective is to understand the relation of tubulin and EHD4 to Na1.5 channel protein remodeling observed in border zone cells (IZs) when arrhythmias are known to occur; that...
2.
Chauveau S, Anyukhovsky E, Ben-Ari M, Naor S, Jiang Y, Danilo Jr P, et al.
Circ Arrhythm Electrophysiol . 2017 May; 10(5):e004508. PMID: 28500172
Background: Although multiple approaches have been used to create biological pacemakers in animal models, induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have not been investigated for this purpose. We now report...
3.
Harleton E, Besana A, Chandra P, Danilo Jr P, Rosen T, Rosen M, et al.
Am J Physiol Heart Circ Physiol . 2014 Dec; 308(2):H126-34. PMID: 25437921
Atrial fibrillation (AF) is a common arrhythmia with significant morbidities and only partially adequate therapeutic options. AF is associated with atrial remodeling processes, including changes in the expression and function...
4.
Dun W, Wright P, Danilo Jr P, Mohler P, Boyden P
PLoS One . 2014 Sep; 9(9):e106830. PMID: 25184222
Because structural remodeling of several proteins, including ion channels, may underlie the abnormal action potentials of Purkinje cells (PCs) that survive in the 48 hr infarcted zone of the canine...
5.
Costet A, Provost J, Gambhir A, Bobkov Y, Danilo Jr P, Boink G, et al.
Ultrasound Med Biol . 2013 Nov; 40(1):177-87. PMID: 24239363
Electromechanical wave imaging (EWI) has been show capable of directly and entirely non-invasively mapping the trans mural electromechanical activation in all four cardiac chambers in vivo. In this study, we...
6.
Boink G, Duan L, Nearing B, Shlapakova I, Sosunov E, Anyukhovsky E, et al.
J Am Coll Cardiol . 2013 Feb; 61(11):1192-201. PMID: 23395072
Objectives: This study sought to test the hypothesis that hyperpolarization-activated cyclic nucleotide-gated (HCN)-based biological pacing might be improved significantly by hyperpolarizing the action potential (AP) threshold via coexpression of the...
7.
Harleton E, Besana A, Comas G, Danilo Jr P, Rosen T, Argenziano M, et al.
J Biol Chem . 2012 Dec; 288(4):2829-38. PMID: 23229553
Peri-operative atrial fibrillation (peri-op AF) is a common complication following thoracic surgery. This arrhythmia is thought to be triggered by an inflammatory response and can be reproduced in various animal...
8.
Ozgen N, Lu Z, Boink G, Lau D, Shlapakova I, Bobkov Y, et al.
Heart Rhythm . 2012 Jul; 9(11):1865-72. PMID: 22820054
Background: Left ventricular pacing (LVP) in canine heart alters ventricular activation, leading to reduced transient outward potassium current (I(to)), loss of the epicardial action potential notch, and T-wave vector displacement....
9.
Boink G, Nearing B, Shlapakova I, Duan L, Kryukova Y, Bobkov Y, et al.
Circulation . 2012 Jul; 126(5):528-36. PMID: 22753192
Background: Biological pacing performed solely via HCN2 gene transfer in vivo results in relatively slow idioventricular rates and only moderate autonomic responsiveness. We induced biological pacing using the Ca(2+)-stimulated adenylyl...
10.
Boink G, Lau D, Shlapakova I, Sosunov E, Anyukhovsky E, Driessen H, et al.
Cardiovasc Res . 2012 Mar; 94(3):450-9. PMID: 22374989
Aims: Reentry accounts for most life-threatening arrhythmias, complicating myocardial infarction, and therapies that consistently prevent reentry from occurring are lacking. In this study, we compare antiarrhythmic effects of gene transfer...