Zhenpeng Zhuang
Overview
Explore the profile of Zhenpeng Zhuang including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
98
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ge W, Gou S, Zhao X, Jin Q, Zhuang Z, Zhao Y, et al.
Signal Transduct Target Ther
. 2024 Jul;
9(1):184.
PMID: 39025833
The CRISPR/Cas9 system has shown great potential for treating human genetic diseases through gene therapy. However, there are concerns about the safety of this system, specifically related to the use...
2.
Lan T, Chen H, Tang C, Wei Y, Liu Y, Zhou J, et al.
Mol Ther Nucleic Acids
. 2023 Sep;
33:890-897.
PMID: 37680986
Prime editor (PE) is a versatile genome editing tool that does not need extra DNA donors or inducing double-strand breaks. However, implementation of PE remains a challenge because of its...
3.
Xie J, Zhuang Z, Gou S, Zhang Q, Wang X, Lan T, et al.
Nucleic Acids Res
. 2023 Aug;
51(18):10075-10093.
PMID: 37650635
None of the existing approaches for regulating gene expression can bidirectionally and quantitatively fine-tune gene expression to desired levels. Here, on the basis of precise manipulations of the Kozak sequence,...
4.
Zhou J, Wang J, Chen F, Zhuang Z, Chen M, Yang Y, et al.
PLoS One
. 2023 Aug;
18(8):e0289509.
PMID: 37540669
Transcription activator-like effectors (TALEs) have been widely used for genome editing, transcriptional regulation, and locus-specific DNA imaging. However, TALEs are difficult to handle in routine laboratories because of their complexity...
5.
Jin Q, Liu X, Zhuang Z, Huang J, Gou S, Shi H, et al.
Genome Biol
. 2023 Jan;
24(1):8.
PMID: 36650523
Background: CRISPR-based toolkits have dramatically increased the ease of genome and epigenome editing. SpCas9 is the most widely used nuclease. However, the difficulty of delivering SpCas9 and inability to modulate...
6.
Li Y, Wang H, Chen H, Liao Y, Gou S, Yan Q, et al.
FASEB J
. 2022 Oct;
36(11):e22611.
PMID: 36250915
Obesity is among the strongest risk factors for type 2 diabetes (T2D). The CREBRF missense allele rs373863828 (p. Arg457Gln, p. R457Q) is associated with increased body mass index but reduced...
7.
Lan T, Zheng Y, Suo Y, Wei Y, Shi H, Yan Q, et al.
J Genet Genomics
. 2022 May;
50(3):212-215.
PMID: 35598861
No abstract available.
8.
Jin Q, Yang X, Gou S, Liu X, Zhuang Z, Liang Y, et al.
Sci China Life Sci
. 2022 May;
65(11):2269-2286.
PMID: 35596888
Inducible expression systems are indispensable for precise regulation and in-depth analysis of biological process. Binary Tet-On system has been widely employed to regulate transgenic expression by doxycycline. Previous pig models...
9.
Liang Y, Xie J, Zhang Q, Wang X, Gou S, Lin L, et al.
Nucleic Acids Res
. 2022 May;
50(9):5384-5399.
PMID: 35544322
Establishing saturated mutagenesis in a specific gene through gene editing is an efficient approach for identifying the relationships between mutations and the corresponding phenotypes. CRISPR/Cas9-based sgRNA library screening often creates...
10.
Li W, Shi L, Zhuang Z, Wu H, Lian M, Chen Y, et al.
J Immunol
. 2021 Sep;
207(9):2385-2386.
PMID: 34580110
No abstract available.