Zachary J Waldrip
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Explore the profile of Zachary J Waldrip including associated specialties, affiliations and a list of published articles.
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7
Citations
77
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Recent Articles
1.
Waldrip Z, Acharya B, Armstrong D, Hanafi M, Rainwater R, Amole S, et al.
Sci Rep
. 2024 Aug;
14(1):19999.
PMID: 39198533
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) plays a vital role in DNA damage repair and lymphocyte function, presenting a significant target in cancer and immune diseases. Current DNA-PKcs inhibitors are...
2.
Azevedo-Pouly A, Appell L, Burdine L, Rogers L, Morehead L, Fil D, et al.
Immunol Cell Biol
. 2023 May;
101(7):663-671.
PMID: 37149747
Modulation of T cell activity is an effective strategy for the treatment of autoimmune diseases, immune-related disorders and cancer. This highlights a critical need for the identification of proteins that...
3.
Waldrip Z, Burdine L, Harrison D, Azevedo-Pouly A, Storey A, Moffett O, et al.
J Biol Chem
. 2021 Sep;
297(4):101209.
PMID: 34562454
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is known primarily for its function in DNA double-stranded break repair and nonhomologous end joining (NHEJ). However, DNA-PKcs also has a critical yet undefined...
4.
Harrison D, Waldrip Z, Burdine L, Shalin S, Burdine M
Transplantation
. 2020 Sep;
105(3):540-549.
PMID: 32890138
Background: Organ transplantation is life-saving and continued investigations into immunologic mechanisms that drive organ rejection are needed to improve immunosuppression therapies and prevent graft failure. DNA-dependent protein kinase catalytic subunit,...
5.
Waldrip Z, Jenjaroenpun P, DeYoung O, Nookaew I, Taverna S, Raney K, et al.
PeerJ
. 2020 Aug;
8:e9442.
PMID: 32821531
The CRISPR system has become heavily utilized in biomedical research as a tool for genomic editing as well as for site-specific chromosomal localization of specific proteins. For example, we developed...
6.
Gao J, Byrd A, Zybailov B, Marecki J, Guderyon M, Edwards A, et al.
Chem Commun (Camb)
. 2019 Mar;
55(31):4467-4470.
PMID: 30855040
We identified 29 G-quadruplex binding proteins by affinity purification and quantitative LC-MS/MS. We demonstrated that the DEAD-box RNA helicases Dbp2, Ded1 and Mss116 preferentially bind to G-quadruplex nucleic acids in...
7.
Waldrip Z, Byrum S, Storey A, Gao J, Byrd A, Mackintosh S, et al.
Epigenetics
. 2014 Aug;
9(9):1207-11.
PMID: 25147920
Any given chromosomal activity (e.g., transcription) is governed predominantly by the local epiproteome. However, defining local epiproteomes has been limited by a lack of effective technologies to isolate discrete sections...