Yu Mashima
Overview
Explore the profile of Yu Mashima including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
77
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Recent Articles
1.
Mashima Y, Nohira H, Sugihara H, Dynlacht B, Kobayashi T, Itoh H
Life Sci Alliance
. 2022 Jul;
5(11).
PMID: 35803737
Clustering of supernumerary centrosomes, which potentially leads to cell survival and chromosomal instability, is frequently observed in cancers. However, the molecular mechanisms that control centrosome clustering remain largely unknown. The...
2.
Kobayashi T, Tanaka K, Mashima Y, Shoda A, Tokuda M, Itoh H
Front Cell Dev Biol
. 2020 Nov;
8:587691.
PMID: 33251215
Primary cilia are hair-like projections that protrude from most mammalian cells and mediate various extracellular signaling pathways. Pancreatic ductal adenocarcinoma (PDAC) cells are known to lose their primary cilia, but...
3.
Kobayashi T, Nakazono K, Tokuda M, Mashima Y, Dynlacht B, Itoh H
EMBO Rep
. 2016 Dec;
18(2):334-343.
PMID: 28028031
Loss of primary cilia is frequently observed in tumor cells, including pancreatic ductal adenocarcinoma (PDAC) cells, suggesting that the absence of this organelle may promote tumorigenesis through aberrant signal transduction...
4.
Yamaguchi A, Mashima Y, Iyoda T
Angew Chem Int Ed Engl
. 2015 Sep;
54(43):12809-13.
PMID: 26331350
This paper describes the reversible control of the size of liquid-metal nanoparticles under ultrasonication. Gallium was utilized as a liquid metal, which has a melting point of 29.8 °C. Investigating...
5.
Mizoi K, Mashima Y, Kawashima Y, Takahashi M, Mimori S, Hosokawa M, et al.
Chem Pharm Bull (Tokyo)
. 2015 Jul;
63(7):538-45.
PMID: 26133069
We discovered that a reagent comprising a combination of PhBCl2 and nitriles was useful for syntheses of both 3-acylindoles and 1-(1H-indol-3-yl)alkylamine from indoles. The reaction proceeded selectively at the 3-position...
6.
Mimori S, Koshikawa Y, Mashima Y, Mitsunaga K, Kawada K, Kaneko M, et al.
Bioorg Med Chem Lett
. 2015 Jan;
25(4):811-4.
PMID: 25595686
The chemical chaperone 4-phenylbutyric acid (4-PBA) has potential as an agent for the treatment of neurodegenerative diseases. However, the requirement of high concentrations warrants chemical optimization for clinical use. In...