Katsuyoshi Mitsunaga
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Explore the profile of Katsuyoshi Mitsunaga including associated specialties, affiliations and a list of published articles.
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17
Citations
71
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Recent Articles
1.
Miyajima A, Kuroda Y, Sakemi-Hoshikawa K, Usami M, Mitsunaga K, Irie T, et al.
Toxicol Rep
. 2020 Sep;
7:979-985.
PMID: 32874920
Effects of 4-methyl-2-mercaptobenzimidazole (4-MeMBI) and 5-methyl-2- mercaptobenzimidazole (5-MeMBI) on cytochrome P450 (CYP) activity were examined in primary cultured rat hepatocytes. Hepatocytes from male Wistar rats were cultured in the presence...
2.
Miyajima A, Sakemi-Hoshikawa K, Usami M, Mitsunaga K, Irie T, Ohno Y, et al.
Biochem Biophys Res Commun
. 2017 Aug;
492(1):116-120.
PMID: 28800917
We examined the effects of thyrotoxic rubber antioxidants, 2-mercaptobenzimidazole (MBI, 0.3 mmol/kg/day) and its methyl derivatives, methyl-MBIs [4-methyl-MBI (4-MeMBI, 0.6 mmol/kg/day), 5-methyl-MBI (5-MeMBI, 0.6 mmol/kg/day), and 4(or 5)-methyl-MBI (4(5)-MeMBI, 0.6...
3.
Usami M, Mitsunaga K, Miyajima A, Takamatu M, Kazama S, Irie T, et al.
Congenit Anom (Kyoto)
. 2015 Jul;
56(2):52-9.
PMID: 26175014
The inhibition of neural crest cell (NCC) migration has been considered as a possible pathogenic mechanism underlying chemical developmental toxicity. In this study, we examined the effects of 13 developmentally...
4.
Mimori S, Koshikawa Y, Mashima Y, Mitsunaga K, Kawada K, Kaneko M, et al.
Bioorg Med Chem Lett
. 2015 Jan;
25(4):811-4.
PMID: 25595686
The chemical chaperone 4-phenylbutyric acid (4-PBA) has potential as an agent for the treatment of neurodegenerative diseases. However, the requirement of high concentrations warrants chemical optimization for clinical use. In...
5.
Usami M, Mitsunaga K, Irie T, Miyajima A, Doi O
Congenit Anom (Kyoto)
. 2014 Apr;
54(3):184-8.
PMID: 24708376
Here, we describe a simple in vitro neural crest cell (NCC) migration assay and the effects of all-trans-retinoic acid (RA) on NCCs. Neural tubes excised from the rhombencephalic or trunk...
6.
Usami M, Mitsunaga K, Irie T, Miyajima A, Doi O
J Toxicol Sci
. 2014 Mar;
39(2):285-92.
PMID: 24646710
Protein expression changes were examined in day 10.5 rat embryos cultured for 24 hr in the presence of ethanol by using two-dimensional electrophoresis and mass spectrometry. Exposure to ethanol resulted...
7.
Usami M, Mitsunaga K, Irie T, Nakajima M
Congenit Anom (Kyoto)
. 2013 Nov;
54(1):67-8.
PMID: 24206169
No abstract available.
8.
Usami M, Mitsunaga K
Expert Rev Proteomics
. 2011 Apr;
8(2):153-5.
PMID: 21501008
Mechanism-based safety evaluation and reduction of animal use are important issues in recent developmental toxicology. In vitro developmental toxicity tests with proteomic analysis are the most promising solution to these...
9.
Usami M, Mitsunaga K, Miyajima A, Sunouchi M, Doi O
Int J Dev Biol
. 2010 Aug;
54(8-9):1277-85.
PMID: 20712003
A presumed embryotrophic factor for early postimplantation rat embryos, partially purified from rat serum, was identified as complement component C3 (C3), the central component of the complement system, by sequence...
10.
Miyajima A, Sunouchi M, Mitsunaga K, Yamakoshi Y, Nakazawa K, Usami M
J Toxicol Sci
. 2009 Dec;
34(6):681-5.
PMID: 19952503
Proteomic analysis of developmental toxicity by two-dimensional electrophoresis (2-DE) may detect gender-related toxic effects in embryos without visible gender characteristics. In the present study, we explored sexing of rat embryo...