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Yu-Le Yong

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Articles 12
Citations 183
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Recent Articles
1.
Wang Y, Li Y, Gao Y, Kang J, Wang W, Yong Y, et al.
Ecotoxicol Environ Saf . 2023 Jun; 262:115134. PMID: 37331288
Epidemiologic studies have demonstrated a direct correlation between fine particulate matter (FPM) exposure and the high risk of respiratory diseases. FPM can penetrate deep into the lung and deposit in...
2.
Zheng N, Zhao X, Wei D, Miao J, Liu Z, Yong Y, et al.
Cancer Lett . 2022 Jun; 542:215762. PMID: 35659513
T cell acute lymphoblastic leukemia (T-ALL) is invasive and heterogeneous, and existing therapies are sometimes unsuccessful. Chimeric antigen receptor (CAR) T cell therapy is a breakthrough tumor treatment method, particularly...
3.
Liu Z, Wu K, Zhang R, Kong L, Shang R, Lv J, et al.
Front Oncol . 2022 Mar; 12:794034. PMID: 35311105
Pyroptosis is an inflammatory form of programmed cell death that is involved in various cancers, including hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) were recently verified as crucial mediators in...
4.
Liu Z, Li C, Zhang R, Wei D, Shang Y, Yong Y, et al.
Mol Cancer . 2021 May; 20(1):79. PMID: 34044846
Background: Somatic mutations are involved in hepatocellular carcinoma (HCC) progression, but the genetic mechanism associated to hepatocarcinogenesis remains poorly understood. We report that Eyes absent homolog 2 (EYA2) suppresses the...
5.
Zhang R, Liu Z, Wei D, Yong Y, Lin P, Li H, et al.
Signal Transduct Target Ther . 2021 Feb; 6(1):64. PMID: 33589597
Genomic sequencing analysis of tumors provides potential molecular therapeutic targets for precision medicine. However, identifying a key driver gene or mutation that can be used for hepatocellular carcinoma (HCC) treatment...
6.
Lv J, Wang H, Cui H, Liu Z, Zhang R, Lu M, et al.
Front Cell Dev Biol . 2021 Jan; 8:609090. PMID: 33490072
The persistence of macrophage-derived foam cells in the artery wall fuels atherosclerosis development. However, the mechanism of foam cell formation regulation remains elusive. We are committed to determining the role...
7.
Li Y, Yong Y, Yang M, Wang W, Qu X, Dang X, et al.
FASEB J . 2020 Oct; 34(12):16716-16735. PMID: 33124742
Mounting evidence from epidemiological and clinical studies has revealed marked correlations between the air pollutant fine particulate matter (FPM) and respiratory diseases. FPM reaches distal airways and deposits in alveolar...
8.
Zhang Z, Lu M, Liu Z, Li H, Yong Y, Zhang R, et al.
Pathol Res Pract . 2020 Aug; 216(9):153046. PMID: 32825931
As a member of the Rab GTPase family, Rab11a plays an important role in vesicle transport and tumor progression. However, it is not clear whether it can also be used...
9.
Zhang R, Wei D, Liu Z, Yong Y, Wei W, Zhang Z, et al.
Front Cell Dev Biol . 2019 Nov; 7:233. PMID: 31681766
Chimeric antigen receptor T cell (CAR-T) therapy to hematological malignancies has demonstrated tremendous clinical outcomes. However, the therapeutic efficacy of CAR-T cells in solid tumors remains limited due to the...
10.
Liu Z, Zhang R, Yong Y, Zhang Z, Li C, Chen Z, et al.
PeerJ . 2019 Aug; 7:e7436. PMID: 31410310
Hepatocellular carcinoma (HCC) is one of the most heterogeneous malignant cancers with no effective targets and treatments. However, the molecular pathogenesis of HCC remains largely uncertain. The aims of our...