Yongwon Choi
Overview
Explore the profile of Yongwon Choi including associated specialties, affiliations and a list of published articles.
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Articles
152
Citations
9623
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Recent Articles
1.
Adamopoulos I, Choi Y, Takayanagi H
Trends Immunol
. 2025 Feb;
PMID: 40011156
Osteoimmunology is an interdisciplinary branch of immunology studying bidirectional interactions between the immune and skeletal systems. Bone marrow is vital for the production of immune cells and is implicated in...
2.
Kim H, Takegahara N, Choi Y
Int J Mol Sci
. 2025 Jan;
26(2).
PMID: 39859288
Protocadherin-7 (Pcdh7) is a member of the non-clustered protocadherin δ1 subgroup within the cadherin superfamily. Pcdh7 has been shown to control osteoclast differentiation via the protein phosphatase 2A (PP2A)-glycogen synthase...
3.
Qin L, Lu J, He Q, Wang H, Yao L, Duffy M, et al.
Res Sq
. 2024 Sep;
PMID: 39257979
Bone resorption by osteoclasts is a critical step in bone remodeling, a process important for maintaining bone homeostasis and repairing injured bone. We previously identified a bone marrow mesenchymal subpopulation,...
4.
Takegahara N, Kim H, Choi Y
Exp Mol Med
. 2024 Jan;
56(2):264-272.
PMID: 38297158
Osteoclasts are the principal cells that efficiently resorb bone. Numerous studies have attempted to reveal the molecular pathways leading to the differentiation and activation of osteoclasts to improve the treatment...
5.
Kim H, Takegahara N, Choi Y
Cells
. 2023 Aug;
12(15).
PMID: 37566044
Protocadherin-7 (Pcdh7) is a member of the non-clustered protocadherin δ1 subgroup of the cadherin superfamily. Pcdh7 has been revealed to control osteoclast differentiation by regulating Rho-family small GTPases, RhoA and...
6.
Kim H, Takegahara N, Choi Y
Bone Res
. 2023 Mar;
11(1):17.
PMID: 36928396
Osteoclasts are primary bone-resorbing cells, and receptor-activated NF-kB ligand (RANKL) stimulation is the key driver of osteoclast differentiation. During late-stage differentiation, osteoclasts become multinucleated and enlarged (so-called "maturation"), suggesting their...
7.
Zhong L, Lu J, Fang J, Yao L, Yu W, Gui T, et al.
Elife
. 2023 Feb;
12.
PMID: 36779854
Colony-stimulating factor 1 (Csf1) is an essential growth factor for osteoclast progenitors and an important regulator for bone resorption. It remains elusive which mesenchymal cells synthesize to stimulate osteoclastogenesis. We...
8.
Takegahara N, Kim H, Choi Y
Bone
. 2022 Feb;
159:116353.
PMID: 35181574
Since the receptor activator of nuclear factor-kappa B ligand (RANKL), its cognate receptor activator of nuclear factor-kappa B (RANK), and the decoy receptor osteoprotegerin (OPG) were discovered, a number of...
9.
Ko K, Merlet J, DerGarabedian B, Zhen H, Suzuki-Horiuchi Y, Hedberg M, et al.
Sci Transl Med
. 2022 Feb;
14(630):eabj0324.
PMID: 35108061
Skin is composed of diverse cell populations that cooperatively maintain homeostasis. Up-regulation of the nuclear factor κB (NF-κB) pathway may lead to the development of chronic inflammatory disorders of the...
10.
Kim H, Takegahara N, Choi Y
Int J Mol Sci
. 2021 Dec;
22(23).
PMID: 34884920
Protocadherin-7 (Pcdh7) is a member of the non-clustered protocadherin δ1 subgroup of the cadherin superfamily. Although the cell-intrinsic role of Pcdh7 in osteoclast differentiation has been demonstrated, the molecular mechanisms...