Yonghoon Kwon
Overview
Explore the profile of Yonghoon Kwon including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
779
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0
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Recent Articles
1.
Park S, Oh A, Hong B, Shin Y, Jang H, Seo H, et al.
Mol Ther Oncol
. 2024 Oct;
32(4):200875.
PMID: 39351074
Alternative splicing products of AIMP2 and AIMP2-DX2 (DX2) have been reported to be associated with human lung cancer. In fact, DX2 expression is elevated in human lung cancers, and DX2...
2.
Shin H, Baek Y, Lee D, Xu Y, Kwon Y, Jo I, et al.
J Microbiol
. 2023 Dec;
61(12):1033-1041.
PMID: 38117463
Escherichia coli RclA and Staphylococcus aureus MerA are part of the Group I flavoprotein disulfide reductase (FDR) family and have been implicated in the contribution to bacterial pathogenesis by defending...
3.
Son Y, Hwang H, Kwon Y
ACS Chem Biol
. 2023 Jan;
18(2):265-272.
PMID: 36693003
Micrococcin P1 and P2 are thiopeptides with a wide range of biological functions including antibacterial and antimalarial activities. We previously demonstrated optimized enzymatic sequences for the exclusive and scalable biosynthesis...
4.
Kwon Y, Mehta S, Clark M, Walters G, Zhong Y, Lee H, et al.
Nature
. 2022 Oct;
611(7934):173-179.
PMID: 36289326
G-protein-coupled receptors (GPCRs), the largest family of signalling receptors, as well as important drug targets, are known to activate extracellular-signal-regulated kinase (ERK)-a master regulator of cell proliferation and survival. However,...
5.
Baek Y, Woo T, Ahn J, Lee D, Kwon Y, Park B, et al.
Commun Biol
. 2022 Oct;
5(1):1085.
PMID: 36224351
Eukaryotic Cu, Zn-superoxide dismutase (SOD1) is primarily responsible for cytotoxic filament formation in amyotrophic lateral sclerosis (ALS) neurons. Two cysteine residues in SOD1 form an intramolecular disulfide bond. This study...
6.
Kwon Y, Kim D, Jeong M, Hong M, Park S, Chang Y, et al.
Cell Chem Biol
. 2022 Sep;
29(10):1532-1540.e5.
PMID: 36167077
Dimerization of beta 2-adrenergic receptor (β-AR) has been observed across various physiologies. However, the function of dimeric β-AR is still elusive. Here, we revealed that dimerization of β-AR is responsible...
7.
Woo T, Yoon M, Kang S, Park S, Cho J, Hwang Y, et al.
Commun Biol
. 2021 Dec;
4(1):1397.
PMID: 34912047
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective death of motor neurons. Mutations in Cu, Zn-superoxide dismutase (SOD1) causing the gain of its toxic property are...
8.
Hwang H, Son Y, Kim D, Lee J, Shin Y, Kwon Y, et al.
Org Biomol Chem
. 2021 Dec;
20(9):1893-1899.
PMID: 34908070
We report the first total synthesis of micrococcin P2 (MP2, 1) by a diversity-oriented route that incorporates a number of refinements relative to earlier syntheses. Biological data regarding the activity...
9.
Cho J, Park S, Kim S, Kang S, Woo T, Yoon M, et al.
Mol Cancer Res
. 2021 Nov;
20(3):412-424.
PMID: 34728553
Implications: This study identifies that a selective RKIP inducer inhibits tumor growth and promotes schwannoma cell differentiation under NF2-deficient conditions by reducing SOX2 and increasing SOX10 expression.
10.
Kim D, Chang Y, Park S, Jeong M, Kwon Y, Zhou K, et al.
Chem Sci
. 2021 Jul;
12(25):8660-8667.
PMID: 34257864
Multicolor fluorescence imaging is a powerful tool visualizing the spatiotemporal relationship among biomolecules. Here, we report that commonly employed organic dyes exhibit a blue-conversion phenomenon, which can produce severe multicolor...